Search for dissertations about: "FoxP3 T-cells"
Showing result 1 - 5 of 83 swedish dissertations containing the words FoxP3 T-cells.
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1. Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease
Abstract : Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. READ MORE
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2. T-cell responses to Helicobacter pylori in humans and a possible role of regulatory T cells
Abstract : Helicobacter pylori colonize the stomach and areas of gastric metaplasia in the duodenum. The bacteria induce both local and systemic immune responses, but despite this, the infection normally persists for life and causes chronic gastritis in all infected subjects and peptic ulcers or gastric cancer in 10-20% of infected individuals. READ MORE
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3. T cells in chronic obstructive pulmonary disease
Abstract : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. READ MORE
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4. On the induction and function of Foxp3+ regulatory T cells
Abstract : This thesis is based on three original papers with the overall aim to study the mechanisms of induction and function of Foxp3+CD4+CD25+ regulatory T cells. Regulatory T cells induce down-modulation of costimulatory molecules CD80 and CD86 on dendritic cells in vitro. READ MORE
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5. Regulatory T cells in human pregnancy
Abstract : During pregnancy, fetal tolerance has to be achieved without compromising the immune integrity of the mother. CD4+CD25highFoxp3+ regulatory cells (Tregs) have received vast attention as key players in immune regulation. However, the identification of human Tregs is complicated by their similarity to activated nonsuppressive T cells. READ MORE