Search for dissertations about: "Fractures: therapy"
Showing result 1 - 5 of 37 swedish dissertations containing the words Fractures: therapy.
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1. Following the mevalonate pathway to bone heal alley
Abstract : The mevalonate pathway is an important biosynthetic pathway, found in all cells of virtually all known pro- as well as eukaryotic organisms. This thesis is an investigation into the use of two drugs, originally developed for different applications, but both affecting the mevalonate pathway, in to models of fracture repair. READ MORE
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2. Hip fracture prevention by screening and intervention of elderly women in primary health care
Abstract : Hip fracture prevention by screening and intervention of elderly women in Primary Health Care Daniel Albertsson Background – One in four Swedish women suffers a hip fracture (HF). In order to identify high-risk women we developed clinical 4-item scores as the FRAMO (Fracture and Mortality) Index, evaluated heel bone mineral density (BMD) and undertook interventions to improve mobility, reduce falls and HF. READ MORE
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3. Hormone replacement therapy : benefits and adverse effects
Abstract : Background: Numerous studies have shown that estrogen replacement therapy (ERT) is an effective treatment for vasomotor symptoms, insomnia and vaginal dryness. Beneficial effects have also been shown on lipid patterns and on the incidence of osteoporotic fractures. READ MORE
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4. Osteogenesis Imperfecta : Genetic and Therapeutic Studies
Abstract : Osteogenesis imperfecta (OI) is a heterogeneous disease of connective tissue, the cardinal symptom being fractures and severity ranging from mild to lethal. Dominant mutations in collagen I, encoded by COL1A1 and COL1A2, cause >90% of cases. READ MORE
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5. Hypertension, atherosclerosis and fracture risk - observational investigations with focus on antihypertensive therapy
Abstract : Aim: To investigate associations between hypertension, arteriosclerotic disease, and fracture risk in adults and the elderly, with a certain focus on how specific antihypertensive drug treatments in patients with high blood pressure might affect the risk for fractures. Methods and results: In Study I and II, the associations between different antihypertensive treatments and fracture risk were investigated in a cohort of about 60. READ MORE