Search for dissertations about: "Francisella tularensis"
Showing result 6 - 10 of 27 swedish dissertations containing the words Francisella tularensis.
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6. Mechanisms of the intracellular survival of Francisella tularensis
Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE
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7. Characterization of the attenuated Francisella tularensis strain FSC043 : with special focus on the gene pdpC
Abstract : Francisella tularensis is a highly infective, intracellular bacterium. It is capable of infecting a wide range of mammals and causes the disease tularemia in humans. As a result of its high infectivity there have been a lot of efforts made to create a generally available vaccine against this pathogen. READ MORE
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8. Determining the role of guanylate-binding proteins for host defense against Francisella tularensis
Abstract : Francisella tularensis is a highly virulent, intracellular bacterium and the causative agent of the human disease tularemia. This is a zoonotic, often vector-borne disease. Due to its intracellular nature, F. READ MORE
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9. Reactive oxygen and nitrogen in host defence against Francisella tularensis
Abstract : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. READ MORE
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10. Genetic genealogy and epidemiology of Francisella
Abstract : This thesis is about analyzing genetic differences among isolates of Francisella tularensis – the tularemia-causing bacterium. To elucidate how these bacterial isolates are related, and their geographical and genetic origins, I have developed typing assays for Francisella and used them to study the epidemiology of tularemia. READ MORE