Search for dissertations about: "Fred van Leuven"
Found 1 swedish dissertation containing the words Fred van Leuven.
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1. Modeling Amyloid-β Pathology in Alzheimer’s Disease Using the Arctic Mutation
Abstract : The Arctic mutation in the Amyloid-β (Aβ) domain of the Amyloid-β precursor protein (APP) causes Alzheimer’s disease (AD) and confers unique biochemical characteristics to Aβ peptides. The aims of this thesis were to evaluate a transgenic model with the Arctic mutation, and to use it to gain new insights into the mechanisms of early (pre-plaque) and late-stage Aβ pathogenesis in AD. READ MORE
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