Search for dissertations about: "Fredrik Bergh Thorén"

Found 2 swedish dissertations containing the words Fredrik Bergh Thorén.

  1. 1. Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance

    Author : Fredrik Bergh Thorén; Göteborgs universitet; []
    Keywords : reactive oxygen species; cell death; apoptosis; poly ADP-ribose polymerase-1; apoptosis-inducing factor; natural killer cells; phagocytes; dendritic cells;

    Abstract : Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is characterized by recurring bacterial infections and thus manifesting the importance of reactive oxygen species in host defense against bacteria. READ MORE

  2. 2. NK Cell Cytotoxicity at the Single Cell Level

    Author : Ludwig Brandt; Björn Önfelt; Fredrik Bergh Thorén; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Abstract : Natural killer (NK) cells are innate immune cells with the ability to recognize and eliminate virally infected cells and cancer cells without prior sensitization. There is a functional heterogeneity between individual NK cells, where some NK cells are more efficient at killing cancer cells than others. READ MORE