Search for dissertations about: "Fredrik Ivars"

Found 5 swedish dissertations containing the words Fredrik Ivars.

  1. 1. Molecular dissection of established and proposed members of the Op18/Stathmin family of tubulin binding proteins

    Author : Kristoffer Brännström; Martin Gullberg; Fredrik Ivars; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Op18 Stathmin; Sm16; tubulin; microtubule; schistosoma mansoni; Molecular biology; Molekylärbiologi;

    Abstract : My initial aim was a functional analysis of the conserved Op18/stathmin family of microtubule-regulators, which includes the ubiquitous cytosolic Op18 protein and the neural membrane-attached RB3 and SCG10 proteins. The solved X-ray structure has shown that these proteins form a complex with tubulin -heterodimers via two imperfect helical repeats, which result in two head-to-tail aligned heterodimers in a tandem-tubulin complex. READ MORE

  2. 2. T-cell Differentiation and Immunological Homeostasis in Lymphopenic and Kappa Light Chain Deficient Mice

    Author : Frida Ekholm Pettersson; Fredrik Ivars; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; T cells; differentiation; homeostasis; cytokines; mice; SCID; κ-deficient; Biokemi; Biochemistry; Biokemi; immunologi; Immunology;

    Abstract : T lymphocytes are primarily involved in adaptive, cell-mediated, immune reactions. In this thesis T cells were studied regarding central and peripheral differentiation and homeostatic mechanisms for maintanance of the immune repertoire.The influence by mature T cells on thymic development was studied in C. READ MORE

  3. 3. Analytical and numerical approaches to estimate peak shear strength of rock joints

    Author : Francisco Ríos Bayona; Stefan Larsson; Fredrik Johansson; Diego Mas Ivars; José Muralha; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Rock joint; Shear strength; Failure criterion; Numerical shear tests; Bergsprickor; Skjuvhållfasthet; Brottkriterium; Numeriska skjuvförsök; Byggvetenskap; Civil and Architectural Engineering;

    Abstract : In Sweden, there exists a large number of dams. Many of them are founded on rock masses normally affected by the presence of sub-horizontal rock fractures, which makes sliding along rock joints under the dam foundation one of the most critical failure mechanism. READ MORE

  4. 4. Peak Shear Strength of Rock Joints – Towards a Methodology for Prediction Based on Field Data

    Author : Francisco Ríos Bayona; Fredrik Johansson; Diego Mas Ivars; Stefan Larsson; José Muralha; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Rock joints; peak shear strength; DEM; matedness; aperture; Bergssprickor; skjuvhållfasthet; DEM; sprickans passning; sprickvidd; Jord- och bergmekanik; Soil and Rock Mechanics;

    Abstract : The rock joint shear strength at field scale is an important design parameter and remains a challenge for rock mechanics engineers. In Sweden, there exist a large number of concrete dams that are founded on rock masses which in many cases contain sub-horizontal rock joints. READ MORE

  5. 5. Quality aspects in direct shear testing of rock joints

    Author : Jörgen Larsson; Fredrik Johansson; Alejano Leandro; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; rock joints; geometrical quality assurance; replicas; direct shear testing; normal stiffness; bergssprickor; geometrisk kvalitetssäkring; replikor; skjuvhållfasthetprovning; normalstyvhet.; Jord- och bergmekanik; Soil and Rock Mechanics;

    Abstract : The stability of rock masses is influenced by the occurrence of rock joints. Therefore, the shear strength of rock joints must be considered in dimensioning of underground constructions. READ MORE