Search for dissertations about: "Fredrik Piehl"

Found 3 swedish dissertations containing the words Fredrik Piehl.

  2. 1. Regulation of CGRP expression in rat spinal motoneurons

    Author : Fredrik Piehl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : immunohistochemistry; in situ hybridization; motoneuron; axotomy; peptides; CGRP; trophic factor; FGF; IGF; BDNF; CNTF; GAP-43; cell culture; plasticity; mRNAregulation; regeneration;

    Abstract : The normal distribution and lesion-induced changes in the expression of neuropeptides and growth-related proteins, with special reference to calcitonin gene-related peptide (CGRP),were studied in the motor system of the rat. In addition, factors that influence the expression of CGRP in motoneurons were identified. READ MORE

  4. 2. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

    Author : Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
    Keywords : Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

    Abstract : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. READ MORE

  5. 3. Quantitative MRI Biomarkers of Neurodegeneration in Multiple Sclerosis

    Author : Michael Platten; Tobias Granberg; Chunliang Wang; Fredrik Piehl; Sara Shams; Mattias Vågberg; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Machine learning; Multiple sclerosis; Corpus callosum; Neurodegeneration; Medical Technology; Medicinsk teknologi;

    Abstract : Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of heavily myelinated axons. READ MORE