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Showing result 1 - 5 of 149 swedish dissertations matching the above criteria.
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1. Free fatty acids and insulin hypersecretion studied in human islets
Abstract : Free fatty acid (FFA) levels are increased in many obese subjects. High FFA levels stimulate the pancreatic beta-cells but have negative long-term effects. In obese children with high FFA levels circulating insulin concentration is high early in life but decline with age precipitating the development of type 2 diabetes mellitus (T2DM). READ MORE
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2. Chemo-Enzymatic Epoxidation of Unsaturated Fatty Acids
Abstract : Epoxy fatty acids are useful molecules and find a number of applications e.g. as PVC plasticisers and stabilisers, additives in polyurethane production, reactive diluents in paints, corrosion protection agents, etc. READ MORE
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3. Effects of Free Fatty Acids on Insulin and Glucagon Secretion : – with special emphasis on the role of Free fatty acid receptor 1
Abstract : Prevalence of type 2 diabetes mellitus (T2DM) is still rising and even so in the juvenile population. Obesity is highly associated with increased risk for developing T2DM. READ MORE
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4. Short- and long-term effects of long-chain free fatty acids on pancreatic α- and β-cell function
Abstract : We have investigated the in vitro effects of long-chain free fatty acids (FFAs) on mouse pancreatic α- and β-cells by a combination of electrophysiological recordings, intracellular Ca2+ ([Ca2+]i) microfluorimetry and hormone release measurements. Acute addition of the saturated FFA palmitate to intact islets doubled insulin as well as glucagon secretion in the presence of 1 or 15 mM glucose and the FFA remained capable of enhancing release of both hormones in islets depolarised with high K+ in the presence of the KATP channel opener diazoxide, indicating that alterations of ATP sensitive potassium (KATP) channel activity is not part of the effect. READ MORE
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5. Effect of Wood Constituents Oxidation of Unsaturated Fatty Acids
Abstract : This work presents the mechanisms of free radicals in a model system between fatty acids oxidation process and wood components. The aim is to create a better understanding of new environmentally friendly materials for exterior wood protection. READ MORE