Search for dissertations about: "Frizzled"
Showing result 1 - 5 of 24 swedish dissertations containing the word Frizzled.
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1. Analysis of Wnt ligands and Fz receptors in Ecdysozoa : Investigating the evolution of segmentation
Abstract : .... READ MORE
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2. Novel insights into dishevelled and frizzled function
Abstract : The formation of a multicellular body during embryonic development is one of the most fascinating processes in biology. The cells are in constant communication and must be precisely coordinated. Several essential signalling pathways have been identified in cell-to-cell signal transmission. READ MORE
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3. WNT/Frizzled signaling : illuminating the road towards pathway selectivity
Abstract : Cells sense and respond to their environment via receptors embedded in the plasma membrane. Receptors allow flow of information from outside to the inside of the cell and are generally regulated by extracellular molecules and proteins, known as ligands. READ MORE
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4. Molecular aspects of WNT/Frizzled signalling in brain angiogenesis
Abstract : The family of WNT lipoglycoproteins consists of 19 secreted proteins that are important for multiple cellular processes including cell proliferation, migration and fate. WNTs induce signalling cascades by binding the seven transmembrane receptors named Frizzleds (FZDs) classified as G protein-coupled receptors (GPCRs). READ MORE
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5. A frizzled quest to dissect the molecular pharmacology of WNT signaling : from biology to signaling mechanism(s)
Abstract : The wingless/int1 (WNT)/Frizzled (FZD) family of signal transduction pathways is highly conserved across species and controls essential physiological functions important for embryonic development, stem cell renewal, proliferation, differentiation, and cell polarity. Dysregulation of these signaling pathways leads to developmental abnormalities or other conditions such as inflammation, cancer, or neurological disorders. READ MORE
