Search for dissertations about: "Frontotemporal lobar degeneration"

Showing result 1 - 5 of 7 swedish dissertations containing the words Frontotemporal lobar degeneration.

2. 1. Molecular Mechanisms of Frontotemporal Lobar Degeneration

   Author : Lena Skoglund; Anna Glaser; Martin Ingelsson; Lars Lannfelt; Stuart Pickering-Brown; Uppsala universitet; []
   Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Frontotemporal lobar degeneration; Frontotemporal dementia; Tau; Progranulin; Alternative splicing; Nonsense-mediated decay; Haploinsufficiency;

   Abstract : The aim of this thesis was to identify genetic factors involved in frontotemporal lobar degeneration (FTLD), a neurodegenerative disorder clinically characterised by a progressive change in personality, behaviour and language. FTLD is a genetically complex disorder and a positive family history is found in up to 40% of the cases. READ MORE

4. 2. Frontotemporal dementia - symptoms and brain pathology

   Author : Maria Landqvist; Lund Psykiatri; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetics; neuropsychiatric symptoms; protein pathology; clinical diagnosis; neuropathology; biomarkers; Frontotemporal dementia;

   Abstract : Frontotemporal dementia (FTD) is the clinical term for a heterogeneous group of dementia disorders with symptoms emerging from frontotemporal lobar degeneration (FTLD). FTD encompasses the behavioural variant (bvFTD) and the progressive aphasias: progressive non-fluent aphasia (PNFA) and semantic dementia (SD). READ MORE

5. 3. Neuropathological findings and staging in dementia

   Author : Hans Brunnström; Tumörmikromiljö; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer disease; concordance; dementia; diagnostics; frontotemporal lobar degeneration; grading; Lewy body disease; locus coeruleus; neuropathology; prevalence; staging; vascular dementia;

   Abstract : Dementia is a clinical syndrome with the development of impairment in multiple cognitive functions (including memory), severe enough to interfere with activities of daily living, as the main symptom. There are a large number of disorders that can lead to dementia, and neuropathological examination after death is necessary to determine the underlying cause with certainty. READ MORE

6. 4. On characterisation and diagnosis of frontotemporal lobar degeneration syndromes : with special reference to the progressive aphasias

   Author : N Christian Andersen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Alzheimer's disease (AD) is the most common dementing brain disease, with episodic memory impairment as a characteristic early feature. However, not all primary degenerative brain syndromes include prominent deficits in day-to-day memorizing. READ MORE

7. 5. The aging frontal lobe in health and disease : a structural magnetic resonance imaging study

   Author : Olof Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cortical and subcortical regions of the brain decrease in volume in normal as well as pathological aging. Previous studies indicate that certain parts of the brain, like the prefrontal cortex, may be particularly vulnerable to age-related processes which are manifested by significant volume loss in this region. READ MORE