Search for dissertations about: "Function parkinson"

Showing result 1 - 5 of 44 swedish dissertations containing the words Function parkinson.

2. 1. The biology of cognitive decline and reduced survival in Parkinson disease : prognostic factors in a population-based cohort

   Author : David C Bäckström; Lars Forsgren; Jan Linder; Niklas Lenfeldt; Jan Aasly; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson disease; multiple system atrophy; progressive supranuclear palsy; natural history; cognitive impairment; dementia; predictors of mortality; cerebrospinal fluid biomarkers; prospective; population-based; Neurology; neurologi;

   Abstract : Parkinson disease (PD) is a progressive neurodegenerative disease that affects about 1% of the population over 60 years. The cardinal symptoms are motor disabilities but cognitive decline is also common. About 50% of all persons with PD develop dementia within 10 years after disease onset. READ MORE

4. 2. Living with Lewy body dementia. Treatment, survival & quality of life

   Author : Victoria Larsson; Klinisk minnesforskning; []
   Keywords : Lewy bodies; Lewy body dementia; Lewy body disease; QUALITATIVE; Lewy Body Disease: drug therapy; Lewy Body Disease: mortality; Lewy Body Disease: therapy; DEMENTIA; dementia with Lewy bodies; Parkinson s disease dementia; Parkinson disease; memantine; Prognosis and survival; Prognosis; Survival; mortality; Dysphagia; Carbonated beverages; Swallowing disorders; Therapeutics; Video recording; video analysing technique; QUALITY OF LIFE;

   Abstract : Background: Patients with Lewy body dementias (LBD) have a complex clinical picture. With no prevention or cure, management focuses around symptomatic relief, however pharmacological and non-pharmacological options have been inadequately investigated. READ MORE

5. 3. Microglial cells in Neurodegenerative Diseases. The Role of Galectin-3

   Author : Antonio Boza Serrano; Neuroinflammation; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; neurosciences; microglia; Galectin-3; Alzheimer disease; Parkinson disease; innate immune system; TLR4; TREM2;

   Abstract : Today, dementia such as, Alzheimer’s disease (AD), vascular diseases and motor neurodegenerative diseases, such as Parkinson’s disease (PD), represent a major public health problem. For instance, PD affect to more than 10 million people worldwide and almost 50 million people are affected by dementia. READ MORE

6. 4. The complex world of proteins: Structure, function, and oligomerization of frataxin

   Author : Christopher Söderberg; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Frataxin; Friedreich s ataxia; self-assembly; protein-protein interaction; iron homeostasis; SAXS; cross-linking;

   Abstract : Patients suffering from the deadly progressive neurodegenerative disease Friedreich's ataxia have reduced levels of expression of the protein frataxin. Yeast frataxin has been extensively studied in vitro, and has been shown to deliver iron to heme and iron-sulfur cluster biosynthesis, as well as to oligomerize in the presence of iron. READ MORE

7. 5. Methods to study glymphatic system in the rodent brain during physiological and pathological processes

   Author : Roberta Battistella; Glia-Immune Interactions; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; Aquaporin-4; Lectins; Parkinson´s disease; α-synuclein; Hypothermia;

   Abstract : Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. READ MORE