Search for dissertations about: "Furosemide"

Showing result 1 - 5 of 14 swedish dissertations containing the word Furosemide.

  2. 1. Inner ear proteomics and barriers : Clinical and experimental findings

    Author : Jesper Edvardsson Rasmussen; Göran Laurell; Per Olof Eriksson; Helge Rask-Andersen; Jonas Bergquist; Måns Magnusson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vestibular schwannoma; Hearing loss; Inner ear; Proteome; Perilymph; Endolymph; Furosemide; NKCC1; Fetuin-A; Complement component factor-H realted protein 2; CFHR2; Inflammation; MRI; Oto-Rhino-Laryngology; Oto-rhino-laryngologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Hearing is important in many aspects of life, including communication, assessing one’s surroundings, entertainment and social interaction. Hearing loss is common and according to the Global Burden of Disease Study, 5% of the global population require hearing rehabilitation (1). READ MORE

  4. 2. Ethanol-mediated effects on astroglial cells in primary culture. With a focus on acute changes in intracellular Ca2+, cell volume, actin filaments, and gap junction coupling

    Author : Louise Adermark; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astrocyte; BaCl2; cell swelling; fura-2; furosemide; ouabain; scrape loading; volume estimation;

    Abstract : The astroglial cells are abundant in the central nervous system (CNS), where they control and regulate the homeostasis of the extracellular milieu. A change in astroglial cell volume, mediated through activation of neuroactive substances or changes in osmolarity, leads to changes in the size and geometry of the extracellular space volume, which could affect the diffusion and concentration of neuroactive substances. READ MORE

  5. 3. The interplay of ions in the stimulation of the pancreatic -cell

    Author : Michael Eberhardson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; pancreatic β-cells; cytoplasmic calcium; oscillations; glucose; tetrodotoxin; tolbutamide; veratridine; tetraethylammonium; quinine; cesium; H2DIDS; furosemide; transients; microfluorometry; fura-2; MQAE; calcium channels; potassium channels; sodium channels; chloride channels; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Glucose stimulation of insulin release is mediated by depolarisation of the pancreatic β-cells with accompanying entry of Ca2+ through voltage-dependent channels. An important feature of the glucose-induced depolarisation is its rhythmicity causing oscillations of the cytoplasmic Ca2+ concentration ([Ca2+]i), which trigger pulsatile release of insulin. READ MORE

  6. 4. The hyperosmolar airway : Mechanisms of reduced response to nitric oxide

    Author : Josephine Hjoberg; Uppsala universitet; []
    Keywords : Medical sciences; 8-Br-cyclic GMP; airway epithelium; airway reactivity; airway smooth muscle; amiloride; epithelium derived relaxing factor; furosemide; hyperosmolarity; hypertonic saline; nitric oxide; SNAP; sodium chloride; sodium nitroprusside; superoxide; tracheal perfusion; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Abstract : Inhaled nitric oxide (NO) relaxes smooth muscle of the airways and of pulmonary blood vessels and is used to treat lung diseases where the pulmonary vessels are constricted. NO has also been tested as a bronchodilator in asthmatic patients. READ MORE

  7. 5. Furosemide dosage input : consequences for diuretic effect, tolerance and efficiency

    Author : Monique Wakelkamp; Karolinska Institutet; Karolinska Institutet; []
    Keywords : furosemide; drug input rate; pharmacokinetics; pharmacodynamics; tolerance; efficiency; probenecid;

    Abstract : The development of new dosage forms raises the question of how the pharmacokinetic pharmacodynamic (PK-PD) profile of a drug is influenced by the drug input rate. Furosemide was used as a model drug to study the relationship between drug input rate and effect. READ MORE