Search for dissertations about: "Fysik med inriktning mot biofysik"

Showing result 1 - 5 of 15 swedish dissertations containing the words Fysik med inriktning mot biofysik.

  1. 1. Femtosecond Dynamics in Water and Biological Materials with an X-Ray Laser

    Author : H. Olof Jönsson; Carl Caleman; Nicusor Timneanu; Olle Björneholm; David van der Spoel; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Using high intensity ultrashort pulses from X-ray free electron lasers to investigate soft matter is a recent and successful development. The last decade has seen the development of new variant of protein crystallography with femtosecond dynamics, and single particle imaging with atomic resolution is on the horizon. READ MORE

  2. 2. Algorithms for Coherent Diffractive Imaging with X-ray Lasers

    Author : Benedikt J. Daurer; Filipe Maia; Tomas Ekeberg; Janos Hajdu; Richard Neutze; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; X-ray lasers; coherent diffractive imaging; algorithms; lensless imaging; flash diffractive imaging; flash X-ray imaging; aerosol injection; FEL; XFEL; CXI; CDI; FXI; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Coherent diffractive imaging (CDI) has become a very popular technique over the past two decades. CDI is a "lensless" imaging method which replaces the objective lens of a conventional microscope by a computational image reconstruction procedure. READ MORE

  3. 3. Imaging Living Cells with an X-ray Laser

    Author : Gijs van der Schot; Tomas Ekeberg; Janos Hajdu; Filipe Maia; Pierre Thibault; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Coherent diffractive X-ray imaging; flash X-ray imaging; lensless imaging; single particle imaging; cyanobacteria; phasing; image classification; substrate-free sample delivery; X-ray free-electron laser; XFEL; FEL; CDXI; CDI; CXI; FXI; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Imaging living cells at a resolution higher than the resolution of optical microscopy is a significant challenge. Fluorescence microscopy can achieve a degree of super-resolution via labeling cellular components with a fluorescent dye. READ MORE

  4. 4. Protein Folding and DNA Origami

    Author : Mark Marvin Seibert; David van der Spoel; Helmut Grubmüller; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; protein folding; Molecular Dynamics simulations; DNA origami; Biophysics; Biofysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : In this thesis, the folding process of the de novo designed polypeptide chignolin was elucidated through atomic-scale Molecular Dynamics (MD) computer simulations. In a series of long timescale and replica exchange MD simulations, chignolin’s folding and unfolding was observed numerous times and the native state was identified from the computed Gibbs free-energy landscape. READ MORE

  5. 5. Gas-Phase Protein Structure Under the Computational Microscope : Hydration, Titration, and Temperature

    Author : Erik Marklund; David van der Spoel; Albert Heck; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Molecular dynamics; gas phase; proteins; micelles; proton transfer; Grothuss mechanism; kinetics; Physics; Fysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Although the native environment of the vast majority of proteins is a complex aqueous solution, like the interior of a cell, many analysis methods for assessing chemical and physical properties of biomolecules require the sample to be aerosolized; that is, transferred to the gas-phase. An important example is electrospray-ionization mass spectrometry, which can provide a wide range of information about e. READ MORE