Search for dissertations about: "Fysik med inriktning mot biofysik"

Showing result 11 - 15 of 16 swedish dissertations containing the words Fysik med inriktning mot biofysik.

  2. 11. Ultrafast Structural and Electron Dynamics in Soft Matter Exposed to Intense X-ray Pulses

    Author : Olof Jönsson; Carl Caleman; Nicusor Timneanu; Olle Björneholm; Jörgen Larsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray free-electron laser; Serial Femtosecond Crystallography; Radiation Damage; Plasma Simulations; Ultrafast Lasers; X-ray Imaging; Diffraction Theory; Ultrafast Phenomena; Hit Detection; Plasma Emission Spectra; Serial Femtosecond Crystallography; Protein Structure; Protein Crystallography; Metalloprotein; Non-thermal Heating; Water; Ferredoxin; NLTE Simulation; XFEL; FEL; SFX; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Investigations of soft matter using ultrashort high intensity pulses have been made possible through the advent of X-ray free-electrons lasers. The last decade has seen the development of a new type of protein crystallography where femtosecond dynamics can be studied, and single particle imaging with atomic resolution is on the horizon. READ MORE

  4. 12. Simulations of Biomolecular Fragmentation and Diffraction with Ultrafast X-ray Lasers

    Author : Christofer Östlin; Carl Caleman; Nicusor Timneanu; Helmut Grubmüller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray free-electron laser; X-ray imaging; Single particle imaging; Computer simulation; Radiation damage; Molecular dynamics; Diffraction theory; Coulomb explosion; Sample heterogeneity; Diffractive noise; XFEL; SPI; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Studies of biomolecules have recently seen substantial developments. New X-ray lasers allow for high-resolution imaging of protein crystals too small for conventional X-ray crystallography. Even structures of single particles have been determined at lower resolutions with these new sources. READ MORE

  5. 13. Alexandria: A General Drude Polarizable Force Field with Spherical Charge Density

    Author : Mohammad Mehdi Ghahremanpour; David Van der Spoel; Kresten Lindorff-Larsen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular mechanics; Force field; Drude oscillator model; Alexandria library; GROMACS; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Molecular-mechanical (MM) force fields are mathematical functions that map the geometry of a molecule to its associated energy. MM force fields have been extensively used for an atomistic view into the dynamic and thermodynamics of large molecular systems in their condensed phase. READ MORE

  6. 14. Towards Fast and Robust Algorithms in Flash X-ray single-particle Imaging

    Author : Jing Liu; Stefan Engblom; Filipe Maia; Janos Hajdu; Helmut Grubmüller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray Free Electron lasers XFELs ; 3D electron density determination; Machine learning; Image processing; High-performance computing; GPUs; Uncertainty quantification; X-ray single-particle Imaging; Flash X-ray single-particle diffraction Imaging FXI ; ; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Modern X-ray Free Electron Laser (XFEL) technology provides the possibility to acquire a large number of diffraction patterns from individual biological nano-particles, including proteins, viruses, and DNA. Ideally, the collected data frames are high-quality single-particle diffraction patterns. READ MORE

  7. 15. Polymer and Protein Physics : Simulations of Interactions and Dynamics

    Author : Anna Sinelnikova; Johan Nilsson; Carl Caleman; Erik Lindahl; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; polymers; proteins; Monte Carlo; molecular dynamics; phase diagram; renormalisation group; SPI; polymer effective model; coarse-graining; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Proteins can, without any exaggeration, be called the "building blocks of life". Their physical properties depend not only on the chemical structure but also on their geometric shape. In this thesis, I investigate protein geometry using several different methods.We start with a coarse-graining model to study the general behavior of polymers. READ MORE