Search for dissertations about: "Fysik med inriktning mot biofysik"

Showing result 6 - 10 of 16 swedish dissertations containing the words Fysik med inriktning mot biofysik.

  2. 6. Gas-Phase Protein Structure Under the Computational Microscope : Hydration, Titration, and Temperature

    Author : Erik Marklund; David van der Spoel; Albert Heck; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular dynamics; gas phase; proteins; micelles; proton transfer; Grothuss mechanism; kinetics; Physics; Fysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Although the native environment of the vast majority of proteins is a complex aqueous solution, like the interior of a cell, many analysis methods for assessing chemical and physical properties of biomolecules require the sample to be aerosolized; that is, transferred to the gas-phase. An important example is electrospray-ionization mass spectrometry, which can provide a wide range of information about e. READ MORE

  4. 7. Statistical processing of Flash X-ray Imaging of protein complexes

    Author : Alberto Pietrini; Carl Nettelblad; Johan Bielecki; Janos Hajdu; Flavio Capotondi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray; XFEL; single particle; hit-finder; statistical hit-finder; single protein; protein complex; RNA polymerase II; FEL; free-electron laser; FXI; Flash X-ray Imaging; CXI; CSPAD; x-ray imaging; COACS; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Flash X-ray Imaging (FXI) at X-ray Free Electron Lasers (XFELs) is a promising technique that permits the investigation of the 3D structure of molecules without the need for crystallization, by diffracting on single individual sample particles.In the past few years, some success has been achieved by using FXI on quite large biological complexes (40 nm-1 μm in diameter size). READ MORE

  5. 8. Flash Diffractive Imaging in Three Dimensions

    Author : Tomas Ekeberg; Janos Hajdu; Keith Nugent; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray; diffraction; mimivirus; three dimensional; phase retrieval; EMC; manifold embedding; CXI; FEL; free-electron laser; single particle; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : During the last years we have seen the birth of free-electron lasers, a new type of light source ten billion times brighter than syncrotrons and able to produce pulses only a few femtoseconds long. One of the main motivations for building these multi-million dollar machines was the prospect of imaging biological samples such as proteins and viruses in 3D without the need for crystallization or staining. READ MORE

  6. 9. Small Particles with Big Impact : Structural Studies of Viruses and Toxicological Studies of Nanodiamonds

    Author : Anna Munke; Marvin Seibert; Kenta Okamoto; Filipe Maia; Inger Andersson; Nicola Stonehouse; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Chaetenuissarnavirus II; cryo-EM; CtenRNAV-II; Escherichia coli; Danio rerio; flash X-ray imaging; Marnaviridae; single-particle analysis; single-particle imaging; Sogarnavirus; virus evolution; virus structure; XFEL; zebrafish embryo; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Nanoparticles (NPs) can be found everywhere and their existence has both beneficial and harmful consequences for the environment and living beings. The investigations on which this thesis is based upon have contributed to an increased understanding of some of these particles and to the development of a method that could be used to study their structure. READ MORE

  7. 10. Protein Folding Simulations in Kink Model

    Author : Xubiao Peng; Antti Niemi; Ulrich Hansmann; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; kink model; soliton; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : The structure of protein is essentially important for life activities. Proteins can perform their functions only by specific structures. In this thesis, the kink and multi-kink model for protein description are reviewed. READ MORE