Search for dissertations about: "G2 M"

Showing result 11 - 15 of 62 swedish dissertations containing the words G2 M.

  2. 11. Physiology and productivity of serum-free Spodoptera frugiperda Sf9 insect cell cultures

    Author : Eva Lindskog; Lena Häggström; Spiros N. Agathos; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Animalcellteknologi; Bioengineering; Bioteknik;

    Abstract : The objective of this study was to investigate the mechanisms and factors controlling growth and proliferation in serum-free Spodoptera frugiperda Sf9 cultures as well as the implications of these factors for protein production in the baculovirus expression system. The physiology of recently thawed, low passage (Lp) Sf9 cultures, were compared to high passage (Hp) cultures at p>100. READ MORE

  4. 12. Myc-induced Lymphomagenesis : In vivo assessment of downstream pathways

    Author : Sara Rimpi; Jonas Nilsson; Juha Klefström; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Myc; lymphomagenesis; Aurora kinases; polyamine; glycolysis; targeting; mouse models of cancer; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Myc oncogenes encode transcription factors that bind to E-box sequences in DNA, driving the expression of a large number of target genes and are deregulated in approximately 70% of human cancers. Deregulated Myc expression cause enhanced proliferation (which is counteracted by apoptosis), angiogenesis and cancer. READ MORE

  5. 13. PHYSIOLOGICAL AND BIOMECHANICAL FACTORS DETERMINING CROSS-COUNTRY SKIING PERFORMANCE

    Author : Erik Andersson; Hans-Christer Holmberg; Glenn Björklund; Thomas Stöggl; Jos J. de Koning; Mittuniversitetet; []
    Keywords : cycle characteristics; energy cost; energy yield; incline; joint angles; kinematics; kinetics; mechanics; Nordic skiing; oxygen deficit; oxygen demand; technique transitions; total metabolic rate.;

    Abstract : Cross-country (c.c.) skiing is a complex sport discipline from both physiological and biomechanical perspectives, with varying course topographies that require different proportions of the involved sub-techniques to be utilised. A relatively new event in c. READ MORE

  6. 14. Ribosomal Proteins in Diamond-Blackfan Anemia : Insights into Failure of Ribosome Function

    Author : Jitendra Badhai; Niklas Dahl; Anthony Wright; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diamond-Blackfan anemia; RPS19; Ribosomal proteins; Haploinsufficiency; cell cycle; Apoptosis; Erythropoiesis; Medical genetics; Medicinsk genetik; Clinical Genetics; klinisk genetik;

    Abstract : Diamond-Blackfan anemia (DBA) is a severe congenital anemia characterized by a defect in red blood cell production. The disease is associated with growth retardation, malformations, a predisposition for malignant disease and heterozygous mutations in either of the ribosomal protein (RP) genes RPS7, RPS17, RPS19, RPS24, RPL5, RPL11 and RPL35a. READ MORE

  7. 15. Regulation of normal and cancer cells as a base for cell cycle-targeted therapy

    Author : Regina Miftakhova; Malmö Experimentell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell cycle regulation; cyclin A1; stem cells; stem cell niche; epigenetics; cancer;

    Abstract : The majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. READ MORE