Search for dissertations about: "G2 M"

Showing result 6 - 10 of 62 swedish dissertations containing the words G2 M.

  2. 6. Structural maintenance of chromsomes : a complex tale of genomic integrity

    Author : Hanna Betts Lindroos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Genomic integrity is an absolute requirement for cell survival. Programmed events such as genome rearrangements and DNA replication can cause lesions in the DNA, as can exogenous agents such as radiation and chemicals. One of the most austere types of lesion is DNA double strand breaks (DBSs). READ MORE

  4. 7. Impact of autocrine factors on physiology and productivity in Trichoplusia ni serum-free cultures

    Author : Ulrika Eriksson; Lena Häggström; Per Berglund; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Trichoplusia ni; High Five; insect cells; BEVS; serum-free medium; yeast extract; conditioned medium; autocrine regulation of proliferation; growth factors; cell cycle; metalloproteinase; specific productivity; Bioteknik; Bioengineering; Bioteknik;

    Abstract : The aim of this study was to increase the understanding of the mechanisms regulating cell proliferation and recombinant protein production in serum-free cultures of Trichoplusia ni (T. ni) insect cells.Conditioned medium (CM) was shown to contain both stimulatory and inhibitory factors (CM factors) influencing cell growth. READ MORE

  5. 8. Antitumor Activities of 2-Methoxyestradiol on Cervical and Endometrial Cancers In Vitro and In Vivo

    Author : Li Li; Xin Fu; Mats Brännström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; 2-Methoxyestradiol; HeLaS3 cells; HEC-1-A cells; RL-95-2 cells; cervical cancer; endometrial cancer; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar;

    Abstract : 2-Methoxyestradiol (2-ME), a metabolite of 17β-estradiol, is a potent antitumor and antiangiogenesis agent in vitro and in vivo. This study aimed to investigate the effects of 2-ME on human cervical and endometrial cancers in vitro and in vivo. READ MORE

  6. 9. Cell cycle and differentiation in Giardia Lamblia

    Author : David S Reiner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Giardia lamblia is the major cause of waterborne diarrhea worldwide. Giardiasis is initiated by ingestion of cysts, which after passing through the stomach are triggered to excyst. Excystation, or awakening from dormancy, is central to successful colonization of the host. READ MORE

  7. 10. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths

    Author : Theres Lindgren; David Eriksson; Torgny Stigbrand; Bo Stenerlöw; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitotic catastrophe; senescence; cell cycle checkpoint; apoptosis; radiation; gene expression; p53; immunologi; Immunology; radiofysik; radiation physics;

    Abstract : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. READ MORE