Search for dissertations about: "G2 checkpoint"
Showing result 1 - 5 of 13 swedish dissertations containing the words G2 checkpoint.
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1. Intrinsic radiosensitivity and molecular targets for tumour radiosensitization of head and neck cancer. With special reference to chromosomal instability and pentoxifylline
Abstract : .... READ MORE
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2. Regulation of G2 phase and long-term consequences of DNA damage
Abstract : Cell proliferation requires the accurate replication of DNA and equal segregation of replicated genes, important for maintaining the integrity of newly formed cells. At the centre of this process is a series of coordinated events termed ‘the cell cycle’, which ensures cell proliferation proceeds with high fidelity. READ MORE
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3. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths
Abstract : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. READ MORE
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4. Cell cycle regulation and DNA damage response : a record of polo-like kinase 1 activity
Abstract : Division and cell proliferation is an essence of life. A human cell has in its core a very simple yet a very complex machinery to coordinate cell cycle activities and events. READ MORE
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5. Tracing the interplay between cellular metabolism and cell cycle
Abstract : Cancer cells are more vulnerable to targeting during S-G2-M cell cycle phases due to common deregulations in cell cycle checkpoint mechanisms. Most common cancer drugs target processes in the S-G2-M phases, often causing negative effects on proliferating normal cells. READ MORE