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Showing result 1 - 5 of 88 swedish dissertations matching the above criteria.

  2. 1. GABA-steroid effects in healthy subjects and women with polycystic ovary syndrome

    Author : Helena Hedström; Torbjörn Bäckström; Marie Bixo; Ian Milsom; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; isoallopregnanolone; gonadotropins; GABA-A receptor; women; polycystic ovary syndrome; saccade; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Background: The progesterone metabolite allopregnanolone is involved in several clinical conditions in women, e.g. premenstrual dysphoric disorder. It is a very potent GABA-steroid with GABA-A receptor effects similar to other GABA-agonists, e. READ MORE

  4. 2. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement

    Author : Mahinda Kommalage; Urban Höglund; Ernst Brodin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; acetylcholine release; spinal antinociception; nicotinic receptor; serotonin; GABA; Neurovetenskap; Neurology; Neurologi;

    Abstract : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. READ MORE

  5. 3. Hippocampal galanin and acetylcholine in spatial learning

    Author : Pär A Schött; Karolinska Institutet; Karolinska Institutet; []
    Keywords : hippocampus; galanin; acetylcholine; memory and learning; swim maze; microinjections; HPLC;

    Abstract : The aim of the present thesis was to study how the neuropeptide galanin affects the neurochemistry and functional activity of the cholinergic septohippocampal projection, which plays a pivotal role in learning and memory. This cholinergic system is strongly impaired in Alzheimer's disease and in age-related dementias. READ MORE

  6. 4. Cyanide and central nervous system : a study with focus on brain dopamine

    Author : Gudrun Cassel; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

    Abstract : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. READ MORE

  7. 5. Chemical signalling in the Drosophila brain : GABA, short neuropeptide F and their receptors

    Author : Lina E. Enell; Dick Nässel; Jonathan Bacon; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Insect nervous system; Drosophila; GABA; sNPF; GPCR; ion channel receptor; feeding; metabolic stress; olfaction; antennal; lobe; mushroom body; Morphology; Morfologi; funktionell morfologi; Functional Zoomorphology;

    Abstract : Gamma-aminobutyric acid (GABA) and short neuropeptide F (sNPF) are widespread signalling molecules in the brain of insects. In order to understand more about the signalling and to some extent start to unravel the functional roles of these two substances, this study has examined the locations of the transmitters and their receptors in the brain of the fruit fly Drosophila melanogaster using immunocytochemistry in combination with Gal4/UAS technique. READ MORE