Search for dissertations about: "GABA A receptor"

Showing result 16 - 20 of 88 swedish dissertations containing the words GABA A receptor.

2. 16. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

   Author : Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

   Abstract : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). READ MORE

4. 17. Tolerance and antagonism to allopregnanolone effects in the rat CNS

   Author : Sahruh Turkmen; Inga-Maj Johansson; Agneta Nordberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; GABA-A receptor; UC1011; Spatial memory; Morris Water Maze; Tolerance; Silent second; mRNA; Obstetrics and gynaecology; Obstetrik och gynekologi;

   Abstract : Many studies have suggested a relationship between sex steroids and negative mental and mood changes in women. Allopregnanolone, a potent endogenous ligand of the GABA-A receptor and a metabolite of progesterone, is one of the most accused neuroactive steroids. READ MORE

5. 18. Regulation of insulin producing cells, stress responses and metabolism in Drosophila

   Author : Neval Kapan; Dick R. Nässel; Alberto Ferrus; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Insulin signaling; Drosophila melanogaster; peptide hormones; neuropeptides; GABA; funktionell zoomorfologi; Functional Zoomorphology;

   Abstract : In Drosophila, neuropeptides have regulatory roles in development, growth, metabolism and reproduction. This study focused on GABA and the neuropeptides Drosophila tachykinin (DTK), short neuropeptide F (sNPF), adipokinetic hormone (AKH), corazonin (CRZ) and Drosophila insulin-like peptides (DILPs) as possible regulators of metabolic stress responses and homeostasis. READ MORE

6. 19. Patch-clamp studies of the GABAA receptor using microfluidic methods

   Author : Maria Millingen; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channel; microfluidics; GABAA receptor;

   Abstract : Ion channels are membrane proteins that passively transport ions. When activated, conformational changes within the protein lead to opening of a channel pore, and the flow of ions causes a change in the membrane potential. This is the fundamental process behind the generation and transduction of nerve impulses. READ MORE

7. 20. Central nervous system targets for micturition control

   Author : Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

   Abstract : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. READ MORE