Search for dissertations about: "GAP-43"

Showing result 16 - 20 of 21 swedish dissertations containing the word GAP-43.

  2. 16. Spinal motoneurons and molecules related to neurotrophic function after axon injury

    Author : Henrik Hammarberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : immunohistochemistry; in situ hybridization; spinal cord; motoneuron; axotomy; survival; regeneration; MHC 1; leukocyte; cell culture; mRNA expression;

    Abstract : The capacity of motoneurons to survive and regenerate new axons after injuries such as axotomy depends on a great variety of parameters. After sciatic nerve transection (SNT) in adult rats and to some extent after a ventral funiculus lesion (VFL), many cells survive and regeneration is highly prioritized. READ MORE

  4. 17. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease

    Author : Maja Puchades; Göteborgs universitet; []
    Keywords : Alzheimer s disease; cerebrospinal fluid; proteomics; mass spectrometry; biomarkers; synaptic proteins; liquid phase IEF; biomarkers;

    Abstract : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. READ MORE

  5. 18. Subacromial inflammation : Clinical and experimental studies

    Author : Carsten Hoe-Hansen; Andris Kreicbergs; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Shoulder pain and disability are common clinical problems. One major cause is subacromial inflammation and impingement of the supraspinatus tendon. These patients are usually offered conservative treatment or arthroscopic subacromial decompression (ASD). READ MORE

  6. 19. Transplantation of mesenchymal stem cells and injections of microRNA as therapeutics for nervous system repair

    Author : Mallappa K. Kolar; Lev N. Novikov; Paul J. Kingham; Mikael Wiberg; Elisabet Åkesson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spinal cord injury; peripheral nerve injury; mesenchymal stem cells; regeneration; neurotrophic factor; angiogenic factor;

    Abstract : Traumatic injuries to the spinal cord (SCI) and peripheral nerve (PNI) affect several thousand people worldwide every year. At present, there is no effective treatment for SCI and despite continuous improvements in microsurgical reconstructive techniques for PNI, many patients are still left with permanent, devastating neurological dysfunction. READ MORE

  7. 20. Elimination of synapses from injured motoneurons : a model for study of synaptic plasticity in the adult central nervous system

    Author : Alexander Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Synapses are the contacts between nerve cells or between nerve and muscle cells. The integrity of these synapses is crucial for proper function. Several neurodegenerative diseases such as Alzheimer’s disease, multiple sclerosis and neurotrauma involve synaptic pathology. READ MORE