Search for dissertations about: "GAS5"

Found 1 swedish dissertation containing the word GAS5.

2. 1. Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis

   Author : Jones Ofori; Diabetes - öcellsexocytos; []
   Keywords : T2D; insulin secretion; exocytosis; ncRNAs; GAS5; miR-152; miR-335; miR-130a b; miR-375; STXBP1; SNAP25; SYT13; PDHA1; PDX1; glucocortiocoid; beta cell function; glucose metabolism;

   Abstract : Type 2 diabetes (T2D) is a complex polygenic disease influenced by both environmental and genetic factors resulting in impaired insulin release from pancreatic beta cells and insulin resistance in target tissues. The incidence of T2D is escalating and it is projected that over 640 million people will be affected by 2040. READ MORE