Search for dissertations about: "GENETIC FACTORS IN MULTIPLE SCLEROSIS"

Showing result 1 - 5 of 73 swedish dissertations containing the words GENETIC FACTORS IN MULTIPLE SCLEROSIS.

  2. 1. Investigation of genetic factors in multiple sclerosis

    Author : Izaura Lima Bomfim; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic disease where the transmission of signals in the central nervous system is affected leading to a broad range of symptoms. The aetiology of the disease is unknown but multiple genetic and environmental factors are believed to play a part. READ MORE

  4. 2. Environmental risk factors for the occurrence of multiple sclerosis

    Author : Martin Biström; Peter Sundström; Johan Hultdin; Jonatan Salzer; Kjell-Morten Myhr; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; risk factors; epidemiology; case-control study; Human herpesvirus 6A; Human herpesvirus 6B; leptin; insulin; Epstein-Barr virus; vitamin D; Neurology; neurologi;

    Abstract : Background. Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system that typically debuts around age 30. About 2.3 million people are affected in the world today, and besides trauma it is the most common cause of neurological disability among young adults in the western world. READ MORE

  5. 3. HLA genetics in multiple sclerosis

    Author : Jenny Link; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. READ MORE

  6. 4. Genetic Analyses of Multiple Sclerosis and Systemic Lupus Erythematosus : From Single Markers to Genome-Wide Data

    Author : Johanna K Sandling; Ann-Christine Syvänen; Lovisa Lovmar; Joseph Terwilliger; Javier Martín Ibáñez; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; Multiple Sclerosis; Association study; Type I interferon system; Single nucleotide polymorphism; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Abstract : In autoimmune diseases an individual’s immune system becomes targeted at the body’s own healthy cells. The aim of this thesis was to identify genetic risk factors for the two autoimmune diseases multiple sclerosis (MS) and systemic lupus erythematosus (SLE). READ MORE

  7. 5. Biomarkers and viral risk factors in multiple sclerosis

    Author : Jesse Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease resulting in axonal injury and demyelination of nerve fibers in the central nervous system. The causal factor and pathological mechanisms governing disease progression have remained elusive, limiting the available clinical tools for MS diagnosis and treatment monitoring, particularly in the periphery. READ MORE