Search for dissertations about: "GH"

Showing result 1 - 5 of 160 swedish dissertations containing the word GH.

  1. 1. Proliferative and protective effects of the GH/IGF-I axis on cardiomyocytes and neural progenitor cells

    Author : Inger Johansson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : GH; IGF-I; GH secretagogues; Ghrelin; Cardiovascular; Neurogenesis; Hippocampus; Proliferation; Protection;

    Abstract : Cardiovascular disease is the most common cause of mortality in the Western world and the majority of cardiovascular deaths are caused by coronary artery disease or cerebrovascular disease. Growth hormone (GH) is a growth-promoting hormone synthesized by the pituitary. READ MORE

  2. 2. Metabolic Effects of Growth Hormone Replacement Therapy in Adults - with Special Reference to Insulin Sensitivity

    Author : Mikael Segerlantz; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; Endokrinologi; sekretion; diabetologi; cortisol replacement; lipid oxidation; glucose metabolism; glucose uptake; insulin resitance; GH; insulin sensitivity; GH deficiency;

    Abstract : A risk for premature atherosclerosis and increased cardiovascular mortality has been reported in adult patients suffering from growth hormone deficiency (GHD) and receiving conventional hormone substitution without growth hormone (GH) replacement. GHD patients are resistant to insulin, which is a potential risk factor for cardiovascular mortality. READ MORE

  3. 3. Effects of GH and liver-derived IGF-I on growth and metabolism

    Author : Klara Sjögren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH; IGF-I; Insulin; GHRH; Somatostatin; GHS; Body growth; Body composition; Liver; Bone mineral content; Bone mineral density.;

    Abstract : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. READ MORE

  4. 4. Keratinocyte differentiation. Involvement of the growth hormon (GH)/insulinlike growth factor1 (IGFI) axis and IGF1 post receptor signaling

    Author : Elisabeth Björntorp Mark; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : IGF1R; GH; Id1; keratinocytes; psoriasis;

    Abstract : At cellular level, little is known about the genes that regulate keratinocyte differentiation andproliferation. Psoriasis is regarded as a T-cell mediated inflammatory disease with hyperproliferativekeratinocytes. READ MORE

  5. 5. The growth hormone receptor and growth hormone sensitivity in man

    Author : Ruth Wickelgren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : GH sensitivity; GH receptor; quantitative RT-PCR; IGF-I; skeletal muscle; adipose tissue; tissue-specific; promoter; 5´-untranslated region; psoriasis; epidermis;

    Abstract : It is well established that the response to endogenous and exogenous growth hormone (GH) varies between individuals. For example, conditions with increased catabolic rate, such as trauma, sepsis and surgery, are believed to be associated with acquired GH insensitivity. READ MORE