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Showing result 1 - 5 of 20 swedish dissertations matching the above criteria.

  2. 1. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

    Author : Linda Ahlkvist; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve; GPR119; Insulin resistance; Glucagon; GIP; GLP-1; Insulin;

    Abstract : There are many contributing factors to the development of type 2 diabetes, however, failure of beta-cells to sufficiently secrete insulin is the key component. The underlying mechanism of beta-cell failure is not fully established. In this thesis, we examined the role of high glucagon levels, i.e. READ MORE

  4. 2. Incretin Hormone Secretion - Studies in Human Subjects

    Author : Ola Lindgren; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; obesity; GLP-1; GIP; incretin;

    Abstract : Several different hormones are released from the intestine following a meal. In this thesis we have focused on the so called incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). READ MORE

  5. 3. Gastric Inhibitory Polypeptide in the brain

    Author : Jenny Nyberg; Göteborgs universitet; []
    Keywords : neural progenitor cells; neural stem cells; hippocampus; cell proliferation; GIP; neuropeptides; insulinotropic; gastrointestinal;

    Abstract : The hippocampus is an area of active cell proliferation and neurogenesis within the adult mammalian brain. Adult neurogenesis is of great importance for the brain, since it increases neuroplasticity and the ability to respond to environmental stimuli. READ MORE

  6. 4. Studies of cAMP and Ca2+ signaling in pancreatic islet cells

    Author : Hongyan Shuai; Anders Tengholm; Erik Gylfe; Sebastian Barg; Albert Salehi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic islet; insulin; glucagon; somatostatin; pancreatic polypeptide; exendin- 9-39 ; GLP-1; GIP; ATP; adenosine; cAMP; Ca2 ; β-cell; α-cell; δ-cell; PP-cell;

    Abstract : The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood. READ MORE

  7. 5. Plant major intrinsic proteins. Identification and characterization of novel water channel-like protiens

    Author : Sofia Gustavsson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; GIP; SIP; GUS; immunolabelling; aquaporin; aquaglyceroporin;

    Abstract : The Major Intrinsic Proteins, MIPs, constitute a large, ancient superfamily of membrane proteins that are found in all kingdoms of life. Most MIPs facilitate passive diffusion of water across biological membranes (aquaporins), although many channels are also permeable for glycerol and other small uncharged solutes, (aquaglyceroporins). READ MORE