Search for dissertations about: "GIP"

Showing result 6 - 10 of 20 swedish dissertations containing the word GIP.

  2. 6. The role of cocaine- and amphetamine-regulated transcript in endocrine cells

    Author : Liliya Shcherbina; Neuroendokrin cellbiologi; []
    Keywords : Type 2 Diabetes; T2D; cocaine and amphetamine-regulated transcript; CART; beta-cell; K-cell; L-cell; insulin; GIP; GLP-1; incretin hormones;

    Abstract : Type 2 diabetes (T2D) is a metabolic disease characterized by insufficient insulin secretion and insulin resistance. Disturbed beta-cell function is the final culprit that leads to the development of T2D. In addition, impaired incretin effect is likely a part of the pathogenesis of T2D. READ MORE

  4. 7. Endocrine aspects of obesity and weight reduction by bariatric surgery : with special emphasis on beta cell function

    Author : Marie Guldstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Obesity; weight reduction; b ariatric surgery; insulin; glucagon; type 2 diabetes; insulin sensitivity; HPA axis; autonomic nervous system ANS ; cognitive functions; proinsulin; GIP; GLP-1; IGFBP- 1; diazoxide;

    Abstract : Severe obesity is the most predictive acquired risk factor for the development of type 2 diabetes. Bariatric surgery induces marked weight loss and reverses the diabetic state significantly. READ MORE

  5. 8. The role of incretin peptides and ghrelin in upper gut motility and metabolic control

    Author : Therese Edholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric emptying rate by gastrointestinal (GI) hormones. READ MORE

  6. 9. Insulinogenic Effects of Milk- and Other Dietary Proteins, Mechanisms and metabolic implications

    Author : Mikael Nilsson; Avdelningen för livsmedel och läkemedel; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Näringslära; Nutrition; Type 2 diabetes; Isolated islets; Incretin hormones; Food proteins; Amino acids; Insulin index; Glycaemic index; Hyperinsulinaemia; Insulin; Blood glucose; Milk; Whey;

    Abstract : The metabolic syndrome (type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, dyslipidaemia, and hyperinsulinaemia), is increasing in prevalence world-wide. The progression of this syndrome proceeds through a step-wise deterioration of metabolic events where deterioration of insulin sensitivity appears to have a key role in a ?vicious circle? of hyperinsulinaemia/hyperglycaemia and insulin resistance. READ MORE

  7. 10. G-proteins and adenylyl cyclase in Alzheimer's disease postmortem brain

    Author : Angela Garcia-Jimnez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer's disease (AD) is the most common type of dementia in the elderly. The major pathological changes seen in the disease are the formation of neurofibrillary tangles, of which the main component is the hyperphosphorylated form of tau, and the over accumulation of plaques formed by beta-amyloid. READ MORE