Search for dissertations about: "GLIAL TUMORS"

Showing result 1 - 5 of 14 swedish dissertations containing the words GLIAL TUMORS.

  2. 1. Pituitary Tumor Surgery - factors influencing outcome

    Author : Tobias Hallén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoscopic transsphenoidal surgery; biomarkers; glial fibrillary acidic protein; neurofilaments; tau protein; pituitary tumors; sinonasal health; tumor progression; predictive markers; MCM7; methylation patterns; NFPA;

    Abstract : Background: Pituitary tumors represent 15–20% of intracranial tumors. The majority are benign adenomas, of which 30 % are hormonally inactive, the non-functioning pituitary adenomas (NFPAs). READ MORE

  4. 2. Stem cell based therapy of malignant brain tumors

    Author : Daniel Bexell; Sektion IV; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; pericyte; mesenchymal stem cell; neuroblast; subventricular zone; cancer stem cell; rat; glioma; cancer;

    Abstract : Malignant brain tumor is a highly invasive and vascularized cancer. Current forms of therapy are not curative and can, at best, prolong survival for patients with this disease. The mean survival is only around 15 months. READ MORE

  5. 3. Cellular Origin and Development of Glioma

    Author : Nanna Lindberg; Lene Uhrbom; Bengt Westermark; Kristian Pietras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

    Abstract : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. READ MORE

  6. 4. Modeling PDGF-driven gliomagenesis in the mouse

    Author : Inga Nazarenko; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Gliomas are the most common form of brain tumors, with glioblastoma being the most aggressive form. Glioblastoma is characterized by a number of genetic aberrations, among them amplification and overexpression of platelet-derived growth factor receptor alpha (PDGFRA) that sometimes occurs together with inactivating mutations or loss of the tumor suppressor p53 (TP53). READ MORE

  7. 5. Towards new tools for clinical evaluation and visualization of tumor growth in patients with glioma

    Author : Kenney Roy Roodakker; Anja Smits; Anne-Marie Landtblom; Elna-Marie Larsson; Jan J. Heimans; Uppsala universitet; []
    Keywords : PROX1; Histology; MRI; PET; Epilepsy; Co-registration; Neurology; Neurologi;

    Abstract : Gliomas are derived from glial cells and are the most common type of primary brain tumors in adults. Gliomas are classified by the World Health Organization (WHO) according to their malignancy grade and histological and molecular features. Malignancy grades range from I to IV. WHO grade I tumors are benign tumors, mostly occurring in childhood. READ MORE