Search for dissertations about: "GLIOMA PATHOLOGY"
Showing result 1 - 5 of 13 swedish dissertations containing the words GLIOMA PATHOLOGY.
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1. Experimental studies on glioma cell motility and proliferation
Abstract : Glioma is a malignant primary brain tumor associated with short patient survival. Various growth factors and cytoskeletal proteins are correlated to glioma progression. In this thesis the effects of transforming growth factor alpha (TGFα) and glial fibrillary acidic protein (GFAP) were studied. READ MORE
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2. Roles of p16INk a and PDGF-B in glioma
Abstract : Gliomas are diffuse astrocytic tumors of the central nervous system (CNS) which usually affect adults. This thesis work has focused on molecular mechanisms of altered growth control in glioma, and the significance of two gene products belonging to pathways commonly affected in glioma, p16INK4a and PDGF-B, has been investigated in vitro and in vivo. READ MORE
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3. Screening for Candidate Brain Tumor Genes : Identifying Genes that Cooperate with Platelet-Derived Growth Factor in Glioma Development and Progression
Abstract : Malignant primary brain tumors, gliomas, often overexpress both platelet-derived growth factor (PDGF) ligands and receptors providing an autocrine and/or paracrine boost to tumor growth. Glioblastoma multiforme (GBM) is the most frequent glioma. Its aggressive and infiltrative growth renders it extremely difficult to treat. READ MORE
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4. Molecular mechanisms involved in glioma cell interactions in vitro and studies of PDGF B transcript variants
Abstract : Glioblastoma multiforme is a malignant brain tumor characterized by heterogeneity.Interactions between heterogeneous tumor cells are supposed to affect the behavior of awhole tumor cell population. READ MORE
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5. Cellular Origin and Development of Glioma
Abstract : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. READ MORE