Search for dissertations about: "GLP-1"

Showing result 1 - 5 of 64 swedish dissertations containing the word GLP-1.

  1. 1. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

    University dissertation from Medicine (Lund)

    Author : Linda Ahlkvist; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve; GPR119; Insulin resistance; Glucagon; GIP; GLP-1; Insulin;

    Abstract : Popular Abstract in Swedish När vi äter socker frisätter kroppen hormonet insulin från specifika beta-celler i bukspottskörteln för att förmå muskelceller och fettceller att ta upp sockret från blodet och därmed återställa blodets sockerbalans. Vid övervikt blir dessa vävnader resistenta mot insulinets verkan vilket leder till att sockret stannar kvar i blodet. READ MORE

  2. 2. IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice

    University dissertation from Medicine (Lund)

    Author : Fredrik Anesten; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-6; IL-6Rα; GLP-1; obesity; hypothalamus; brainstem; tanycytes; immunohistochemistry;

    Abstract : It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ICV- injections, but not peripheral injections of IL-6, increases energy expenditure and decreases body fat in rodents. READ MORE

  3. 3. Role of GLP-1 receptor agonists in endothelial function

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Science and Education, Södersjukhuset

    Author : Özlem Erdogdu; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes;

    Abstract : BACKGROUND: The leading cause of death for patients suffering from type 2 diabetes is macrovascular disease. Endothelial dysfunction is one of the earliest events identified in the pathogenesis of atherosclerosis. Hence, there is a need for finding glucose-lowering agents that cause direct positive effects on vasculature in diabetic patients. READ MORE

  4. 4. Incretin Hormone Secretion - Studies in Human Subjects

    University dissertation from Clinical Sciences, Lund University

    Author : Ola Lindgren; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; obesity; GLP-1; GIP; incretin;

    Abstract : Popular Abstract in Swedish Det finns ett flertal hormoner som bildas i mag-tarmkanalen och som sedan frisätts till blodet i samband med måltidsintag. Runtom i kroppen finns det sedan målceller, så kallade receptorer, som stimuleras av hormonerna till att påverka olika processer i kroppen. READ MORE

  5. 5. Studies of cAMP and Ca2+ signaling in pancreatic islet cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hongyan Shuai; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic islet; insulin; glucagon; somatostatin; pancreatic polypeptide; exendin- 9-39 ; GLP-1; GIP; ATP; adenosine; cAMP; Ca2 ; β-cell; α-cell; δ-cell; PP-cell;

    Abstract : The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood. READ MORE