Search for dissertations about: "GLP-1RA"

Found 4 swedish dissertations containing the word GLP-1RA.

  2. 1. Save the brain! Studies on GLP-1-mediated neuroprotection

    Author : Martin Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Patients with type 2 diabetes (T2D) suffer stroke more often and have worse recovery. Moreover, hyperglycemic stroke patients treated with thrombolytic therapy have more intracranial bleedings. READ MORE

  4. 2. Brain-gut-adipose interplay in the antidiabetic effects of gastric bypass surgery

    Author : Kristina Almby; Jan Eriksson; Bo Ahrén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Medicinsk vetenskap; Medical Science; Medicinsk vetenskap; Medical Science;

    Abstract : Gastric bypass surgery (GBP) leads not only to considerable and consistent weight loss but to a number of beneficial metabolic effects, often including a swift remission of type 2 diabetes (T2DM). Increases in the gut hormone GLP-1 are considered central to this effect, although several other mechanism are likely involved. READ MORE

  5. 3. On cardiovascular complications in people with type 2 diabetes : Aspects of incretin-based therapy and glycemic control

    Author : Irene Santos Pardo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Hyperglycemia, insulin resistance, and the presence of advanced glycation end products are key features of type 2 diabetes (T2DM) and the leading mechanisms behind the increased cardiovascular risk observed in people with this condition. Percutaneous coronary revascularization has been associated with higher risk of stent failure in people with diabetes mellitus (DM), having greater risk of both in-stent restenosis (ISR) and stent thrombosis (ST). READ MORE

  6. 4. Metabolic and endocrine effects of SGLT2 inhibition

    Author : Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
    Keywords : SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Abstract : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. READ MORE