Search for dissertations about: "GM-CSF"

Showing result 1 - 5 of 88 swedish dissertations containing the word GM-CSF.

  2. 1. Granulopoietic growth factors. Cytokine and cellular regulation of GM-CSF and G-CSF production

    Author : Stig Lenhoff; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocytes; endothelial cells; GM-CSF; G-CSF; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : Granulocyte-macrophage- (GM-) and granulocyte- (G-) colony stimulating factor (CSF) are important cytokines in the regulation of hematopoiesis and for the function of mature blood cells. They are also involved in the cytokine network regulating the inflammatory and immune response. READ MORE

  4. 2. GM-CSF. A regulator of pre-implantation embryo development

    Author : Cecilia Sjöblom; Göteborgs universitet; []
    Keywords : GM-CSF blastocyst embryo culture cytokine growth factor GM-CSF receptor glucose transport apoptosis;

    Abstract : GM-CSF is a multifunctional cytokine expressed in abundance in the female reproductive tract during early pregnancy. We have investigated the regulatory influence of GM-CSF in development of pre-implantation mouse and human embryos. READ MORE

  5. 3. Glucocorticosteroid effects on cytokine production: studies in a glucocorticosteroid resistance model and in allergic airway disease

    Author : Susanne Larsson; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GM-CSF; cytokine; glucocorticoids; budesonide; IL-2; IL-4; IL-12; asthma; allergic rhinitis; allergic airway inflammation; Respiratory system; Andningsorganen;

    Abstract : Glucocorticosteroids (GCS) are potent anti-inflammatory drugs, probably due to inhibitory effects on cytokine production. However, a small number of asthma patients seem GCS-resistant. Pro-inflammatory cytokines, such as interleukin-2(IL-2) and IL-4, produced during allergic airway inflammation have been proposed to induce the resistance to GCS. READ MORE

  6. 4. Vaccine Therapy of Colorectal Cancer Patients with Tumor Associated Antigens

    Author : Gustav Ullenhag; Håkan Mellstedt; Carl Magnusson; Bengt Glimelius; Torgny Stigbrand; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Oncology; Colorectal cancer; GM-CSF; vaccination; CEA; ALVAC-KSA; IgG subclass; epitopes; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Abstract : In this thesis, two different vaccines were evaluated as adjuvant therapy for patients with colorectal cancer. The ability of the two candidate vaccines to generate antigen-specific cellular and humoral responses, respectively, was studied. READ MORE

  7. 5. Gene therapy of neuroblastoma

    Author : Yvonne Arvidsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; gene therapy; PNP; ASK1; MASH1; IL-12; GM-CSF; immunotherapy; apoptosis.;

    Abstract : Aims: The survival of children with advanced stages of neuroblastoma has not improved significantly during recent years. Therefore additional treatments based on other modalities need to be developed. The objective of this thesis was to investigate the possibility to develop gene therapy of neuroblastoma. READ MORE