Search for dissertations about: "GRP"

Showing result 1 - 5 of 11 swedish dissertations containing the word GRP.

  2. 1. The neuropeptides GRP and PACAP and the function of the endocrine pancreas - A study on receptor deficient mice

    Author : Kristin Persson; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; hypoglycemia; glucagon; insulin; islet of Langerhans; diabetes; PACAP; neuropeptides; GRP; diabetologi;

    Abstract : The parasympathetic nerves are important for the regulation of insulin secretion, in particular after meal intake. Apart from acetylcholine, several neuropeptides can be found in the parasympathetic nerves innervating the islets of Langerhans, including gastrin-releasing peptide (GRP) and pituitary adenylate cyclase activating polypeptide (PACAP). READ MORE

  4. 2. Neuropeptides and neurotrophins in arthritis : studies on the human and mouse knee joint

    Author : Ola Grimsholm; Sture Forsgren; Solbritt Rantapää-Dahlqvist; Elvar Theodorsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropeptides; neurotrophins; bombesin gastrin-releasing peptide; substance P; brain-derived neurotrophic factor; synovial tissue; knee joint; rheumatoid arthritis; Anatomy; Anatomi;

    Abstract : Neuropeptides, such as substance P (SP) and bombesin/gastrin-releasing peptide (BN/GRP), and neurotrophins are involved in neuro-immunomodulatory processes and have marked trophic, growth-promoting and inflammation-modulating properties. The impact of these modulators in rheumatoid arthritis (RA) is, however, unclear. READ MORE

  5. 3. Groundwater resources in hard rock coastal terrains : Insights into heterogeneity and spatial variability

    Author : Robert Earon; Bo Olofsson; Okke Batelaan; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Crystalline Rock; Groundwater Balance; Kinematic porosity; Groundwater Recharge; Water Security; Coastal Aquifer; Land and Water Resources Engineering; Mark- och vattenteknik;

    Abstract : Challenges regarding water security in hard rock coastal regions with limited soil cover are: a seasonal absence of recharge during times of peak residency, heterogeneity and variability of the fracture network, close proximity to saline water sources and spatially inconsistent storage and extraction. In areas where it is not feasible to connect residents to municipal water systems, a better understanding of the resilience of reservoirs is needed. READ MORE

  6. 4. Origin, release and functional significance of the novel gastric hormone ghrelin

    Author : Charlotta Dornonville de la Cour; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; bone metabolism; energy homeostasis; glucagon; insulin; secretion; pancreastatin; somatostatin; histamine; gastrin; gastric acid secretion; ghrelin; gastric motility; A-like cells; farmakognosi; farmaci; toxikologi;

    Abstract : The novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. READ MORE

  7. 5. Water supply in hard rock coastal regions : The effect of heterogeneity and kinematic porosity

    Author : Robert Earon; Bo Olofsson; Gerhard Barmen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Coastal aquifer; Crystalline rock; Water balance; Geographic information systems; Water supply planning;

    Abstract : Water resources in hard rock terrain are difficult to characterize due to heterogeneity and anisotropy in the fracture network, low porosities and limited recharge volumes available during the summer season. Three methods were developed and evaluated in order to assist in water supply planning. READ MORE