Search for dissertations about: "Gait"

Showing result 1 - 5 of 183 swedish dissertations containing the word Gait.

  1. 1. Structures, toxicity and internalization of cell-penetrating peptides

    Author : Emelía Eiríksdóttir; Ülo Langel; Michael Gait; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPP; cell-penetrating peptide; internalization; toxicity; structures; Neurochemistry; Neurokemi; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Cellular internalization is a highly regulated process controlled by proteins in the plasma membrane. Large and hydrophilic compounds, in particular, face difficulties conquering the plasma membrane barrier in order to gain access to intracellular environment. This puts serious constrains on the drug industry since many drugs are hydrophilic. READ MORE

  2. 2. Cell-penetrating peptides in protein mimicry and oligonucleotide delivery : Applications and mechanisms

    Author : Henrik Johansson; Ülo Langel; Michael Gait; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptide; oligonucleotide; cell-penetrating peptide; PNA; splicing; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : The plasma membrane functions as a barrier, restricting entry of hydrophilic pharmaceutical agents. Cell-penetrating peptides (CPPs) are capable of transporting bioactive cargos into the cell and have consequently been extensively investigated for their mechanism of entry and capability to deliver various cargos spanning from peptides to plasmids. READ MORE

  3. 3. Cell-penetrating peptides and bioactive cargoes : Strategies and mechanisms

    Author : Kalle Kilk; Ülo Langel; Michael J. Gait; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptide; delivery; Peptide nucleic acid; Biochemistry; Biokemi;

    Abstract : The cell membrane is an impermeable barrier for most macromolecules. Recently discovered cell-penetrating peptides (CPPs) have gained lot of attention because they can cross the membrane, and even more, carry cargoes with them. How CPPs enter cells is still not clear, while the delivery of different cargoes has been convincingly shown. READ MORE

  4. 4. Learning Human Gait

    Author : Parinaz Kasebzadeh; Fredrik Gustafsson; Gustaf Hendeby; Linköpings universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Pedestrian navigation in body-worn devices is usually based on global navigation satellite systems (GNSS), which is a sufficient solution in most outdoor applications. Pedestrian navigation indoors is much more challenging. Further, GNSS does not provide any specific information about the gait style or how the device is carried. READ MORE

  5. 5. Gait Event Detection in the Real World

    Author : Siddhartha Khandelwal; Nicholas Wickström; Thorsteinn Rögnvaldsson; Brian Caulfield; Högskolan i Halmstad; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; gait analysis; gait event detection; wearable sensors; accelerometers;

    Abstract : Healthy gait requires a balance between various neuro-physiological systems and is considered an important indicator of a subject's physical and cognitive health status. As such, health-related applications would immensely benefit by performing long-term or continuous monitoring of subjects' gait in their natural environment and everyday lives. READ MORE