Search for dissertations about: "Gal4"

Showing result 1 - 5 of 16 swedish dissertations containing the word Gal4.

  2. 1. Engineering Transcriptional Systems for Cyanobacterial Biotechnology

    Author : Daniel Camsund; Peter Lindblad; Brian Pfleger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; Synthetic biology; promoters; transcription; LacI; Gal4; Light-regulation; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

    Abstract : Cyanobacteria are solar-powered cell factories that can be engineered to supply us with renewable fuels and chemicals. To do so robust and well-working biological parts and tools are necessary. READ MORE

  4. 2. Accumulation and Cellular Clearance of IAPP and Proteotoxicity of ATTR in Drosophila Models

    Author : Xiaohong Gu; Gunilla Westermark; Anders Olofsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; IAPP; ATTR; ATTR amyloidosis; crystalline structure; aggrephagy; Drosophila melanogaster; Gal4-UAS; electron tomography; DAMS; SOHA; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Proteins’ functions are dependent on their three-dimensional (3D) structure. Under certain circumstances, proteins misfold and form aggregates, sometimes leading to amyloidosis. Islet amyloid polypeptide (IAPP) builds up amyloid in the pancreatic islet of patients with type 2 diabetes (T2D). READ MORE

  5. 3. Studies on two transcription regulatory proteins : cellular c-Jun and adenovirus E1A

    Author : Kerstin Sollerbrant; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adenovirus; EIA; EIB; transcription; CtBP; c-Jun; Gal4;

    Abstract : Adenoviruses cause lytic infections in a range of mammalian cells, but can in certain cases also transform the host cell. The first adenovirus gene to be expressed upon infection is E1A. The E1A gene encodes two major proteins of 243 and 289 amino acids, respectively, both of which serve as key regulators during virus infection. READ MORE

  6. 4. Modeling Amyloid Disease in Drosophila melanogaster

    Author : Ina Berg; Per Hammarström; Stefan Thor; Damian Crowther; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Amyloid diseases are caused by protein misfolding and aggregation. To date there are 27 known proteins causing amyloid disorders involving brain and peripheral protein deposition. The proteins involved in this mechanism do not share sequence homology, but the amyloid fibrils share biophysical properties and possibly a common pathogenic mechanism. READ MORE

  7. 5. Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene

    Author : Maria Backlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AhR; omeprazole; primaquine; CYP1A1; ligand-independent activation; ligandbinding domain; protein tyrosine kinase; c-src kinase;

    Abstract : The aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription factor that is responsible for the activation of several response genes, of which the best characterised is the CYP1A1 gene. The prototype high affinity ligand for the AhR is the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). READ MORE