Search for dissertations about: "Ganesh Umapathy"

Found 1 swedish dissertation containing the words Ganesh Umapathy.

2. 1. Oncogenic ALK signaling in neuroblastoma

   Author : Ganesh Umapathy; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaplastic lymphoma kinase; neuroblastoma; ERK5; Akt; MYCN; mTOR;

   Abstract : Over the last decade Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase (RTK) has been identified as a translocation partner in diverse cancer types. In tumors, where the full-length ALK RTK itself is mutated, such as neuroblastoma, the picture is less clear regarding ALKs role as an oncogenic driver. READ MORE