Search for dissertations about: "Gene duplication"

Showing result 1 - 5 of 96 swedish dissertations containing the words Gene duplication.

  1. 1. Evolution of Vertebrate Endocrine and Neuronal Gene Families Focus on Pituitary and Retina

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Daniel Ocampo Daza; Uppsala universitet.; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phylogenetics; evolution; molecular evolution; gene family evolution; genome duplication; gene duplication; oxytocin receptor; vasopressin receptor; visual opsin; transducin; growth hormone; prolactin; somatolactin; growth hormone receptor; prolactin receptor; somatostatin receptor; SSTR; IGFBP; evolution; molekylär evolution; fylogeni;

    Abstract : The duplication of genes followed by selection is perhaps the most prominent way in which molecular biological systems gain multiplicity, diversity and functional complexity in evolution. Whole genome duplications (WGDs) therefore have the potential of generating an extraordinary amount of evolutionary innovation. READ MORE

  2. 2. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Robert Piotr Olinski; Uppsala universitet.; [2007]
    Keywords : Neurosciences; insulin; relaxin; insulin-like protein; gene duplication; paralogous region; Ciona intestinalis; conserved synteny; ortholog; Drosophila melanogaster; Neurovetenskap;

    Abstract : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. READ MORE

  3. 3. Probabilistic Modelling of Domain and Gene Evolution

    University dissertation from Stockholm, Sweden : KTH Royal Institute of Technology

    Author : Sayyed Auwn Muhammad; KTH.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phylogenetics; Phylogenomics; Evolution; Domain Evolution; Gene tree; Domain tree; Bayesian Inference; Markov Chain Monte Carlo; Homology Inference; Gene families; C2H2 Zinc-Finger; Reelin Protein; Computer Science; Datalogi;

    Abstract : Phylogenetic inference relies heavily on statistical models that have been extended and refined over the past years into complex hierarchical models to capture the intricacies of evolutionary processes. The wealth of information in the form of fully sequenced genomes has led to the development of methods that are used to reconstruct the gene and species evolutionary histories in greater and more accurate detail. READ MORE

  4. 4. Evolution of the Neuropeptide Y and Opioid Systems and their Genomic Regions

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Görel Sundström; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropeptide Y; opioid; evolution; genome duplication; gene duplication; Hox; SCN; IGFBP; MEDICINE; MEDICIN;

    Abstract : Two whole genome duplications (2R) occurred early in vertebrate evolution. By using combined information from phylogenetic analyses and chromosomal location of genes, this thesis delineates the evolutionary history of two receptor-ligand systems that expanded by these large scale events. READ MORE

  5. 5. Variation in length of proteins by repeats and disorder regions

    University dissertation from Stockholm, Sweden : Department of Biochemistry and Biophysics, Stockholm University

    Author : Rauan Sagit; Stockholms universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein length; repeats; domain repeats; protein evolution; duplication; tandem duplication; intrinsic disorder; intrinsically disordered; variation in length; insertion; deletion; recombination; expansion; contraction; biokemi; Biochemistry;

    Abstract : Protein-coding genes evolve together with their genome and acquire changes, some of which affect the length of their protein products. This explains why equivalent proteins from different species can exhibit length differences. READ MORE