Search for dissertations about: "Gene-expression"

Showing result 1 - 5 of 1797 swedish dissertations containing the word Gene-expression.

  1. 1. Statistical analysis of gene expression data

    University dissertation from Göteborg : Chalmers University of Technology

    Author : Erik Kristiansson; Göteborgs universitet.; Gothenburg University.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; linear models; categorical data analysis; heavy metal stress; logistic regression; DNA microarrays; empirical Bayes; ecotoxicology; quality control; gene regulation;

    Abstract : Microarray technology has become one of the most important tools for genome-wide mRNAmeasurements. The technique has been successfully applied to many areas in modernbiology including cancer research, identification of drug targets, and categorization of genesinvolved in the cell cycle. READ MORE

  2. 2. Gene expression in carcinogenesis

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Heléne Fischer; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. READ MORE

  3. 3. Nonlinear dimensionality reduction of gene expression data

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Jens Nilsson; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gene expression; Manifold learning; Nonlinear dimensionality reduction; Microarray;

    Abstract : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. READ MORE

  4. 4. Organization of mitochondrial gene expression in yeast Specific features of organellar protein synthesis

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Kirsten Kehrein; Martin Ott; Thomas A Fox; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; biokemi; Biochemistry;

    Abstract : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. READ MORE

  5. 5. Gene Expression Studies of Hematologic Malignacies

    University dissertation from Divison of Clinical Genetics

    Author : Anna Andersson; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; cancer; onkologi; Cytologi; oncology; Cytology; acute myeloid leukemia; acute lymphoblastic leukemia; normal hematopoietic cells; cDNA microarray; gene expression profiling; hematopoiesis; pediatric leukemia; fusion gene; Pediatrics; Pediatri; Clinical genetics; Klinisk genetik; cancerology; Hematologi; extracellulära vätskor;

    Abstract : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. READ MORE