Search for dissertations about: "Genetic Mapping"
Showing result 16 - 20 of 225 swedish dissertations containing the words Genetic Mapping.
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16. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE
Abstract : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. READ MORE
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17. Genetic analysis of autoimmune diseases using animal models : Mapping susceptibility genes for multiple sclerosis and rheumatoid arthritis
Abstract : Autoimmune diseases such as rheumatoid arthritis and multiple sclerosis are common human diseasesaffecting 1% and 0.1% of the population respectively. These diseases are characterized by abnormal self-tolerance in the immune system and autoimmune reactions. READ MORE
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18. Sequence evolution in a chromosomal region of Arabidopsis thaliana
Abstract : Recently there has been a lot of interest in the use of liknage disequilibrium (LD) in genome wide scans for new genes, so called association mapping. Of crucial importance to a genome wide scan for associations between genetic markers and the trait of interest is the extent of LD, as it determines both how closely a trait can be mapped and also how many markers is needed to map it. READ MORE
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19. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches
Abstract : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. READ MORE
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20. Genome mapping of the horse
Abstract : Our ability to map and sequence whole genomes is one of the most important developments in biological science. It will provide us with an unprecedented insight into the genetic background of phenotypic traits, such as disease resistance, reproduction and growth and also makes it feasible to study the processes of genome evolution. READ MORE