Search for dissertations about: "Genetic determinants of dyslipidemia"

Found 2 swedish dissertations containing the words Genetic determinants of dyslipidemia.

2. 1. Genetic Determinants of Dyslipidemia

   Author : Tibor V Varga; Genetisk och molekylär epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetic epidemiology; Genetic polymorphism; dyslipidaemia; Cholesterol; Triglyceride; Genetic risk; genetic risk score; Single nucleotide polymorphism; Prediction; Gene-environment interactions; Randomized controlled trial; prospective cohort studies; Observational study; GLACIER Study; Diabetes Prevention Program;

   Abstract : Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (LDL-C) have a strong genetic underpinning, not much is known about the genetic factors that affect long-term deteriorations in lipid concentrations. READ MORE

4. 2. Lipid-related genes and their associations with coronary heart disease

   Author : Ci Song; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Coronary heart disease (CHD) is a complex disease caused by the long-term progression of atherosclerosis. Lipids, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) are well established biomarkers for CHD, and are used to predict individual 10-year risk for CHD both in the Framingham risk score and in the System for Cardiac Operative Risk Evaluation (SCORE) project. READ MORE