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Showing result 1 - 5 of 1304 swedish dissertations matching the above criteria.
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1. Genetic Determinants of Dyslipidemia
Abstract : Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (LDL-C) have a strong genetic underpinning, not much is known about the genetic factors that affect long-term deteriorations in lipid concentrations. READ MORE
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2. INDIVIDUAL GENETIC RESEARCH RESULTS : Uncertainties, Conceptions, and Preferences
Abstract : This thesis contributes to the ethical discussion on how to handle incidental findings in biomedical research using sequencing technologies from a theoretical and an empirical perspective. Study I and II are theoretical studies that used conceptual analysis. READ MORE
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3. Population genetic analyses in the orchid genus Gymnadenia : a conservation genetic perspective
Abstract : Small populations are facing a particular risk of extinction due to a lack of appropriate genetic diversity and associated negative effects, factors dealt with in the discipline of conservation genetics. Many orchid species exhibit characteristics that make them a perfect study object in the scope of conservation genetics. READ MORE
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4. Psychological and Behavioral Aspects of Receiving Genetic Counseling for Hereditary Cancer
Abstract : The overall aims of this thesis were to investigate psychological and behavioral effects of receiving cancer genetic counseling for breast, ovarian and colorectal cancer and/or with a family history of these cancer types and to determine whether counselees’ informational needs were met. Study I was performed 3-7 years post-counseling. READ MORE
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5. Genetic Risk Factors for Systemic Lupus Erythematosus : From Candidate Genes to Functional Variants
Abstract : The aim of this thesis has been to identify genetic variants that increase the susceptibility for Systemic Lupus Erythematosus (SLE), an autoimmune disease caused by a complex interplay between various genetic and environmental factors. Five different candidate genes were selected through different strategies, and were analysed for association with SLE in an attempt to distinguish some of the underlying mechanisms of this disease. READ MORE