Search for dissertations about: "Genetik"
Showing result 6 - 10 of 1230 swedish dissertations containing the word Genetik.
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6. Expression and function of Suppressor of zeste 12 in Drosophila melanogaster
Abstract : The development of animals and plants needs a higher order of regulation of gene expression to maintain proper cell state. The mechanisms that control what, when and where a gene should (or should not) be expressed are essential for correct organism development. READ MORE
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7. Chromosome-wide gene regulatory mechanisms in Drosophila melanogaster
Abstract : In Drosophila there are two different chromosome-wide targeting systems, the dosage compensation system that equalizes the transcriptional output from X-linked genes between males and females, and the regulation of the 4th chromosome mediated by the POF protein. The best studied of these two mechanisms is the dosage compensation system. READ MORE
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8. Genetic analysis of genes found on the 4th chromosome of Drosophila - emphasizing the developmental context of Pax6
Abstract : The small size and the lack of recombination set the fourth chromosome of Drosophila melanogaster apart from the other chromosomes. I have shown that the Minute gene on chromosome 4, earlier named Minute-4, encodes the ribosomal protein RpS3A. Two Pax6 genes, eyeless (ey) and twin of eyeless (toy) are also located on chromosome 4. READ MORE
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9. Investigation of Mechanics of Mutation and Selection by Comparative Sequencing
Abstract : The process of evolution is of both scientific and medical interest. This thesis presents several studies using complete genomic reference sequences, comparative genomic data, and intraspecific diversity data to study the two key processes of evolution: mutation and selection. READ MORE
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10. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus
Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. READ MORE