Search for dissertations about: "Genotyping"

Showing result 16 - 20 of 266 swedish dissertations containing the word Genotyping.

  2. 16. Dried blood sampling and digital readout to advance molecular diagnostics

    Author : Johan Björkesten; Ulf Landegren; Björn Högberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular diagnostics; dried blood sample; DBS; digital readout; digital enumeration; DNA detection methods; proximity extension assay; protein stability; genotyping; rare mutations; cell free DNA; multiplex protein measurement.; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : A drastically increased capacity to measure large sets of molecular features in numerous patient samples in great detail will be required to fulfill the vision of precision medicine and wellness, which may characterize molecular diagnostics in the 21st century. Also sampling procedures need a renaissance to permit continuous sampling at population levels at reasonable cost. READ MORE

  4. 17. Detection and Characterisation of Salmonella in Animal Feed Samples by PCR-Based Methods

    Author : Charlotta Löfström; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; Livsmedelsteknik; Biotechnology; Bioteknik; Biokemisk teknik; Biochemical technology; Analytisk kemi; Analytical chemistry; mykologi; virologi; bakteriologi; Mikrobiologi; validation; Microbiology; bacteriology; virology; mycology; Salmonella; ribotyping; detection; animal feed; randomly amplified polymorphic DNA; pulsed-field gel electrophorsis; pre-PCR processing; PCR; polymerase chain reaction; genotyping;

    Abstract : Animal feed is a recognised source of Salmonella enterica for farm livestock and may also indirectly cause infection in people consuming foods of animal origin. It is therefore important to have rapid, reproducible and specific methods for the detection of Salmonella in feed, and for the characterisation of strains for further epidemiological investigations or to trace the source of contamination in a production facility. READ MORE

  5. 18. Detection of Chlamydia trachomatis and Mycoplasma genitalium by genetic and serological methods

    Author : Margaretha Jurstrand; Hans Fredlund; Erik Kihlström; Örebro universitet; []
    Keywords : Chlamydia trachomatis; genotyping; contact tracing; sexually transmitted diseases; Mycoplasma genitalium; PCR; serology; MEDICINE; MEDICIN; Medicin; Medicine;

    Abstract : Chlamydia trachomatis infections are associated with a spectrum of clinical diseases including urethritis, prostatitis and epididymitis among men and cervicitis and pelvic inflammatory disease (PID), with an increased risk of infertility and ectopic pregnancy (EP), among women. In the search for other pathogens causing urethritis, Mycoplasma genitalium was isolated from urethral specimens from two men with acute urethritis (1980). READ MORE

  6. 19. Genetic genealogy and epidemiology of Francisella

    Author : Kerstin Svensson; Anders Johansson; Mats Forsman; Sam R. Telford III; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; tularemia; genotyping; epidemiology; GIS; Infectious diseases; Infektionssjukdomar; Infectious Diseases; infektionssjukdomar;

    Abstract : This thesis is about analyzing genetic differences among isolates of Francisella tularensis – the tularemia-causing bacterium. To elucidate how these bacterial isolates are related, and their geographical and genetic origins, I have developed typing assays for Francisella and used them to study the epidemiology of tularemia. READ MORE

  7. 20. Nucleic Acid Based Pathogen Diagnostics

    Author : Michael S. Akhras; Pål Nyrén; Nader Pourmand; Mats Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pathogen diagnostics; antibiotic resistance; connector inversion probes CIPer ; human papillomavirus HPV ; genotyping; global health diagnostic forum; molecular inversion probe MIP ; neisseria gonorrhoeae; padlock probes; pyrosequencing; Biochemistry; Biokemi;

    Abstract : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. READ MORE