Search for dissertations about: "George Tsokos"

Found 1 swedish dissertation containing the words George Tsokos.

2. 1. The Role of Plasmacytoid Dendritic Cells and Natural Killer Cells in Systemic Lupus Erythematosus

   Author : Niklas Hagberg; Lars Rönnblom; Maija-Leena Eloranta; George Tsokos; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; plasmacytoid dendritic cells; natural killer cells; type I interferon; immune complex; SLAM receptors; autoantibodies; CD94 NKG2A; CD94 NKG2C; Medicinsk vetenskap; Medical Science; Immunologi; Immunology;

   Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production, which can eventually lead to immune complex (IC)-mediated organ damage. Due to the stimulation of plasmacytoid dendritic cells (pDC) by nucleic acid-containing ICs (DNA- or RNA-IC), patients with SLE have an ongoing interferon (IFN)-α production. READ MORE