Search for dissertations about: "Gerd Pääjärvi"

Found 1 swedish dissertation containing the words Gerd Pääjärvi.

2. 1. Xenobiotics-induced phosphorylations of MDM2

   Author : Gerd Pääjärvi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The aim of the present study was to characterize the Mdm2 and p53 responses induced by DNA damaging xenobiotics and how these responses can be modified by non-genotoxic xenobiotics. During control conditions cellular levels of p53 are low. The level is regulated by Mdm2 and Mdm2 and p53 forms an autoregulatory loop. READ MORE