Search for dissertations about: "Gingival"

Showing result 1 - 5 of 89 swedish dissertations containing the word Gingival.

  1. 1. Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts

    Author : Tove Båge; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; c-Jun N-terminal kinase;

    Abstract : Periodontitis is a chronic inflammatory disease resulting in the destruction of the tissue and alveolar bone supporting the teeth and leading ultimately to tooth loss. Prostaglandin E2 (PGE2) is an important inflammatory mediator in the pathogenesis of periodontitis. READ MORE

  2. 2. Regulation of prostaglandin E2 synthesis in human gingival fibroblasts

    Author : Tülay Yucel-Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; prostaglandin E2; cyclooxygenase; phospholipase A2 interleukin-1; tumor necrosis factor [alpha]; epidermal growth factor; protein kinase C; tyrosine kinases; human gingival fibroblasts;

    Abstract : Prostaglandins, especially, prostaglandin E2 (PGE2) play an important role in inflammatory diseases such as rheumatoid arthritis and periodontitis. The aim of the present thesis was to study the production and the regulation of PGE2 with special reference to the key enzymes phospholipase A2 (PLA2) and cyclooxygenase (COX) at the rnRNA level in human gingival fibroblasts. READ MORE

  3. 3. Cyclosporin A-induced gingival overgrowth in renal transplant patients : A clinical, histological and experimental study

    Author : Biniyam Wondimu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; cyclosporin A gingival overgrowth gingival fibroblasts nephrotoxicity renal transplant saliva;

    Abstract : Cyclosporine A (CsA) is widely used as an effective immunosuppressive agent to prevent rejection of organ transplants, as well as in the treatment of patients with various autoimmune diseases. The clinical use of CsA, however, is associated with adverse side effects, including nephrotoxicity, hepatotoxicity, hypertension, and neurotoxicity as well as gingival overgrowth. READ MORE

  4. 4. Osteotropic cytokines : expression in human gingival fibroblasts and effects on bone

    Author : Py Palmqvist; Andersson Göran; Umeå universitet; []
    Keywords : osteoblasts; osteoclasts; fibroblasts; cytokines; IL-6; LIF; OSM; IL-4; IL-3; bone resorption; odontologi; Odontology;

    Abstract : Bone metabolism is regulated by endocrine and paracrine signalling molecules influencing bone cells in the continuously remodelling bone tissue. These molecules include a variety of osteotropic stimulatory and inhibitory cytokines. READ MORE

  5. 5. On Oral Health in Young People with Asthma

    Author : Malin Stensson; Dowen Birkhed; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescents; Saliva secretion; Plaque-pH; Oral health; Mouth breathing; Gingival bleeding; Cariogram; Caries; asthma;

    Abstract : Objective. The aim of this thesis was to investigate the oral health of young individuals with and without asthma. Material. In Study I, a group of 3- (n=66) and 6-year-old children (n=61) with asthma and two healthy control groups (n=62 and n=55 respectively) participated. READ MORE