Search for dissertations about: "Gl cell cycle arrest"

Found 4 swedish dissertations containing the words Gl cell cycle arrest.

  2. 1. Studies on the antiproliferative action of interferon : effects on proteins synthesized in the G1 and S phase of the cell cycle in 2 anchorage-dependent cell lines

    Author : Dan Lundblad; Erik Lundgren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon; Glioma; Antiproliferative effect; DNA polymerase; Thymidine kinase; 2 -5 oligo A; Protein synthesis; Two-dimensional electrophorensis; Mouse fibroblasts; C-myc; KI-67 antigen;

    Abstract : Interferons (IFNs) are a class of structurally related proteins first discovered to be produced by virus-infected cells. By now, several other inducing agents have been described. READ MORE

  4. 2. Regulation of the murine immunoglobulin GL gamma-1 and epsilon promoters

    Author : Lena Ström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system takes advantage of different genetic alterations to amplify its diversity. First at early stages of B cell differentiation when the antigen (ag) receptors are assembled from different gene segments. READ MORE

  5. 3. Effects of interferon on cellular proliferation and apoptosis

    Author : Olle Sangfelt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : interferon; malignancy; apoptosis; cell cycle;

    Abstract : Interferon (IFN) therapy is today a well-established treatment in many diseases, including various malignancies. How IFN exerts antitumor activity is not known, but several mechanisms have been suggested. READ MORE

  6. 4. The antagonistic role of activated oncogenes and apoptosis : studies of n-myc and p53 in lymphoid tumorigenesis

    Author : Yisong Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MPC; EmyN-myc transgene; J3D T Iymphoma cells; p53; v-m y cretrovirus; bcl-2; Gl cell cycle arrest; apoptosis; HPV 16 E7;

    Abstract : Inactivation of the p53 tumor suppressor gene and activation of proto-oncogenes have been implicated in the initiation and/or progression of a number of neoplasms. In this thesis, the involvement of N-myc gene activation has been studied in mouse plasmacytomagenesis and the role of wild-type (wt)p53 and oncogene activation has been evaluated with particular emphasis on apoptosis. READ MORE