Search for dissertations about: "Global Proteome Survey"

Found 2 swedish dissertations containing the words Global Proteome Survey.

  2. 1. Global Proteome Survey -Transforming antibody-based affinity proteomics into a global discovery platform

    Author : Niclas Olsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity proteomics; recombinant antibodies; Proteomics; mass spectrometry; proteome profiling; breast cancer; antibody specificity;

    Abstract : Proteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurements. READ MORE

  4. 2. Molecular Portraits of Cancer : Discovery of Biomarker Signatures using Affinity Proteomics

    Author : Petter Skoog; Institutionen för immunteknologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Breast Cancer; Pancreatic cancer; antibody microarray; Immunosignature; Global Proteome Survey; Affinity proteomics; Biomarker;

    Abstract : The use of antibodies as capture molecules in assays is a common practice. By either printing monoclonal single chain fragment variables (scFvs) on a solid support – recombinant antibody microarray – or attaching them to magnetic beads – Global Proteome Survey (GPS) – we can specifically capture and measure target proteins of interest. READ MORE