Search for dissertations about: "Global haemostatic assays"

Found 1 swedish dissertation containing the words Global haemostatic assays.

2. 1. Determination of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials

   Author : Aleksandra Antovic; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Global haemostatic assays; overall haemostasis potential; hypercoagulation; hypocoagulation; thrombophilia; haemophilia; fibrin gel porosity; LMMH therapy; acetylsalicylic acid therapy;

   Abstract : We have previously developed a laboratory method that may screen the Overall Haemostasis Potential (OHP) in plasma based on spectophotometric measurement of an area under the fibrin aggregation curve in citrated plasma samples to which tiny amounts of exogenous thrombin and tissue-plasminogen activator (t-PA) are added. When the fibrin aggregation curve is created, the fibrinogen originally present in plasma is gradually converted to fibrin by the generated thrombin. READ MORE