Search for dissertations about: "Glomerular filtration barrier"

Showing result 21 - 25 of 28 swedish dissertations containing the words Glomerular filtration barrier.

  2. 21. Proteome studies, with emphasis on the kidney glomerulus

    Author : Sam Tryggvason; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Proteomics aims to link genes to protein expression and function. Proteomics is a very versatile and technology-dependent discipline and the development of mass spectrometry-based proteomics has advanced the understanding of the complex and dynamic nature of proteomes. READ MORE

  4. 22. Identification and characterization of kidney glomerulus-associated genes and proteins

    Author : Ljubica Perisic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The kidney glomerulus is a micro-organ comprised of a molecular filtration barrier that prevents the loss of blood proteins into the primary filtrate. This function is dependent on the coordination of its three constituent layers: the endothelium, the glomerular basement membrane and the podocytes. READ MORE

  5. 23. Identification and characterization of novel glomerulus-associated genes and proteins

    Author : Zhijie Xiao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The kidney is responsible for sieving the circulating blood to eliminate water-soluble waste products and potentially toxic substances from the body. The filtration step occurs in specialized filtration units called glomeruli. READ MORE

  6. 24. The role of melanocortin 1 receptor in kidney disease

    Author : Annika Lindskog Jonsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrotic syndrome; proteinuria; adrenocorticotropic hormone; melanocortin 1 receptor; podocytes;

    Abstract : Nephrotic syndrome is a term describing a group of poorly understood glomerular diseases that are responsible for a steadily increasing number of patients requiring active uremic care. Characteristic symptoms of nephrotic syndrome are proteinuria, hypoalbuminemia, hyperlipidemia and peripheral edema, and treatment of these symptoms, rather than their cause, is currently the only option available to the clinician. READ MORE

  7. 25. Type IV collagen : regulation of COL4A1 and COL4A2 genes and gene therapy of Alport syndrome

    Author : Pirkko Kortteinen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adenovirus; Alport syndrome; basement membrane; bidirectional promoter; collagen; gene regulation; gene therapy; promoter analysis; kidney gene transfer; organ perfusion; type IV collagen;

    Abstract : Type IV collagen is an important structural protein in basement membranes, which am thin sheet-like structures located between organized tissues and the connective tissue. Type IV collagen is composed of six genetically different [alpha] chains. READ MORE