Search for dissertations about: "Glucuronidase"

Showing result 1 - 5 of 8 swedish dissertations containing the word Glucuronidase.

  1. 1. Influence of probiotics and other external factors on intestinal biochemical microflora-associated characteristics : Studies in vitro and in vivo in gnotobiotic mice and in pigs

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Maria E Cardona G; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastrointestinal microflora germ-free mice; lactic acid bacteria; microflora- associated characteristics; piglets; probiotics.;

    Abstract : The benefit of harboring a balanced intestinal microflora is well recognized. Therefore, in order to 'maintain or improve the intestinal flora, the use of microbial species as feed supplements, i.e. probiotics, has rapidly increased. READ MORE

  2. 2. Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elina Hjertström; Jin-ping Li; Ulf Lindahl; Sally Stringer; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; Alzheimer s disease; ; Proteoglycan; Heparanase; Amyloid; Hypoxia; Cancer; Spalax; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Heparan sulfate (HS) is a highly sulfated polysaccharide expressed on the cell surface and in the extracellular matrix, interacting with a large number of proteins. HS is implicated in human diseases, including different types of cancer and amyloid diseases such as Alzheimer's disease (AD). READ MORE

  3. 3. Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tianyi Song; Dorothe Spillmann; Cathrine Merry; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; biosynthesis; heparanase; lipid metabolism; cancer; cell adhesion; apoptosis.;

    Abstract : Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. READ MORE

  4. 4. Structural Determination of Drug Metabolites from Doping Classed Compounds Using Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Annelie Hansson; Mikael Hedeland; Ulf Bondesson; Peter Hemmersbach; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectrometry; UHPLC-MS MS; doping control; Cunninghamella elegans; selective androgen receptor modulator; SARM; andarine; ostarine; LGD-4033; roxadustat; HIF stabilizer; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : Doping control in equine sports is important for a fair competition, but also to ensure the integrity of the betting system, as well as for animal welfare reasons. To detect the use of illicit compounds, screening for the parent compound is common. However, by using a metabolite as the analytical target instead, the detection time can be prolonged. READ MORE

  5. 5. Plasma Membrane Proteomics and Functional Characterization & Expression Profiling of Plant Aquaporins

    University dissertation from Department of Biochemistry, Lund University

    Author : Erik Alexandersson; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; phosphorylation; barley; GFP; GUS; quantitative real-time reverse transcriptase PCR; microarray; aquaporin; MIP; Arabidopsis; plasma membrane; proteomics;

    Abstract : In order to identify integral and peripheral proteins associated with the plasma membrane (PM), highly purified Arabidopsis PMs were analyzed by mass spectrometry. In total, 238 putative PM proteins were identified, of which 114 were predicted to have transmembrane domains or to be PM-anchored. READ MORE